Igbp1b immunoglobulin (CD79A) binding protein 1b [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Igbp1bprovided by MGI
Official Full Name: immunoglobulin (CD79A) binding protein 1bprovided by MGI
Primary source: MGI:MGI:1354380
See related: Ensembl:ENSMUSG00000046717 AllianceGenome:MGI:1354380
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: alpha4-b
Summary: Predicted to enable protein phosphatase 2A binding activity and protein phosphatase regulator activity. Predicted to be involved in several processes, including negative regulation of nitrogen compound metabolic process; negative regulation of stress-activated MAPK cascade; and response to interleukin-1. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in bladder; testis; ureter; and urethra of male. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Orthologous to human IGBP1 (immunoglobulin binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 6 G1; 6 69.23 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	6	NC_000072.7 (138634087..138635452, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	6	NC_000072.6 (138657089..138658454, complement)

Chromosome 6 - NC_000072.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:493939

NoName (e-PCR)
- UniSTS:493228

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables phosphatase regulator activity	TAS Traceable Author Statement more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein phosphatase 2A binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within B cell activation	IEA Inferred from Electronic Annotation more info
involved_in regulation of dephosphorylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: immunoglobulin-binding protein 1b

Names: CD79a-binding protein 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.