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Zbtb9 zinc finger and BTB domain containing 9 [ Mus musculus (house mouse) ]

Gene ID: 474156, updated on 5-Mar-2024

Summary

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Official Symbol
Zbtb9provided by MGI
Official Full Name
zinc finger and BTB domain containing 9provided by MGI
Primary source
MGI:MGI:1918022
See related
Ensembl:ENSMUSG00000079605 AllianceGenome:MGI:1918022
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3930402F13Rik
Summary
Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including 1st branchial arch maxillary component; eye; genitourinary system; heart; and hepatic primordium. Orthologous to human ZBTB9 (zinc finger and BTB domain containing 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 18.5), spleen adult (RPKM 9.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
17; 17 A3.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (27192153..27195177)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (26973179..26976203)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E487 Neighboring gene synaptic Ras GTPase activating protein 1 homolog (rat) Neighboring gene microRNA 3083b Neighboring gene cutA divalent cation tolerance homolog Neighboring gene microRNA 3083 Neighboring gene STARR-positive B cell enhancer ABC_E7502 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:27137073-27137182 Neighboring gene STARR-positive B cell enhancer ABC_E11633 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:27164461-27164644 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:27165231-27165340 Neighboring gene gametogenetin binding protein 1 Neighboring gene STARR-seq mESC enhancer starr_42142 Neighboring gene BCL2-antagonist/killer 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:27193173-27193441 Neighboring gene inositol 1,4,5-triphosphate receptor 3 Neighboring gene microRNA 7677

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. An Oct4-centered protein interaction network in embryonic stem cells. van den Berg DLC, et al. Cell Stem Cell, 2010 Apr 2. PMID 20362541, Free PMC Article
  2. Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation. Barnes CE, et al. Mol Omics, 2022 Jan 17. PMID 34709266, Free PMC Article
  3. An atlas of combinatorial transcriptional regulation in mouse and man. Ravasi T, et al. Cell, 2010 Mar 5. PMID 20211142, Free PMC Article
  4. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  5. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Potential readthrough

Included gene: Ggnbp1

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger and BTB domain-containing protein 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005916.2 → NP_001005916.1  zinc finger and BTB domain-containing protein 9

    See identical proteins and their annotated locations for NP_001005916.1

    Status: PROVISIONAL

    Source sequence(s)
    BC049933
    Consensus CDS
    CCDS37520.1
    UniProtKB/Swiss-Prot
    Q3U3B2, Q8CDC7, Q9CYQ0
    Related
    ENSMUSP00000112778.2, ENSMUST00000120016.3
    Conserved Domains (4) summary
    smart00225
    Location:49 → 142
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00017
    Location:374 → 391
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:399 → 419
    zf-C2H2; Zinc finger, C2H2 type
    pfam00651
    Location:38 → 138
    BTB; BTB/POZ domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    27192153..27195177
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CDC7.1 GenPept UniProtKB/Swiss-Prot:Q8CDC7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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