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MT-TG mitochondrially encoded tRNA glycine [ Homo sapiens (human) ]

Gene ID: 4563, updated on 10-Oct-2023

Summary

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Official Symbol
MT-TGprovided by HGNC
Official Full Name
mitochondrially encoded tRNA glycineprovided by HGNC
Primary source
HGNC:HGNC:7486
See related
MIM:590035; AllianceGenome:HGNC:7486
Gene type
tRNA
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MTTG; TRNG
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Genomic context

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Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) MT (non-nuclear) NC_012920.1 (9991..10058)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) MT (non-nuclear) NC_012920.1 (9991..10058)

Chromosome MT - NC_012920.1Genomic Context describing neighboring genes Neighboring gene ATP synthase F0 subunit 8 Neighboring gene ATP synthase F0 subunit 6 Neighboring gene cytochrome c oxidase subunit III Neighboring gene NADH dehydrogenase subunit 3 Neighboring gene tRNA-Arg

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular characterization of a pedigree carrying the hypertension‑associated mitochondrial tRNAGln T4363C mutation. Wang L, et al. Mol Med Rep, 2017 Nov. PMID 28849157, Free PMC Article
  2. Mitochondrial DNA A4336G mutation in Alzheimer's and Parkinson's diseases. García-Lozano JR, et al. Eur Neurol, 2002. PMID 12138308
  3. Mitochondrial tRNA(Glu) A14693G variant may modulate the phenotypic manifestation of deafness-associated 12S rRNA A1555G mutation in a Han Chinese family. Ding Y, et al. J Genet Genomics, 2009 Apr. PMID 19376484
  4. Complex I polymorphisms, bigenomic heterogeneity, and family history in Virginians with Parkinson's disease. Swerdlow RH, et al. J Neurol Sci, 2006 Sep 25. PMID 16784756, Free PMC Article
  5. Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk. Webb E, et al. Br J Cancer, 2008 Dec 16. PMID 19050702, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Molecular characterization of a Chinese pedigree carrying the hypertension-associated mitochondrial tRNAGln T4363C mutation has been reported.
    Title: Molecular characterization of a pedigree carrying the hypertension‑associated mitochondrial tRNAGln T4363C mutation.
  2. Mitochondrial tRNA(Glu) variant modulate the phenotype of deafness-associated 12S rRNA A1555G mutation in Chinese family.
    Title: Mitochondrial tRNA(Glu) A14693G variant may modulate the phenotypic manifestation of deafness-associated 12S rRNA A1555G mutation in a Han Chinese family.
  3. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
    Title: Complex I polymorphisms, bigenomic heterogeneity, and family history in Virginians with Parkinson's disease.
  4. Observational study of gene-disease association. (HuGE Navigator)
    Title: MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

  • NAR: 0797

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases