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LINC02487 long intergenic non-protein coding RNA 2487 [ Homo sapiens (human) ]

Gene ID: 441178, updated on 10-Oct-2023

Summary

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Official Symbol
LINC02487provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 2487provided by HGNC
Primary source
HGNC:HGNC:53466
See related
Ensembl:ENSG00000203688 AllianceGenome:HGNC:53466
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward esophagus (RPKM 19.4) See more
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Genomic context

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Location:
6q27
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (167680691..167696289, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (169018289..169034192, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (168081371..168096969, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378131 Neighboring gene MPRA-validated peak6319 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:168052990-168053978 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:168072861-168073360 Neighboring gene long intergenic non-protein coding RNA 2538 Neighboring gene uncharacterized LOC124901465 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:168085935-168086436 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25459 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25458 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:168103963-168104504 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:168108302-168109023 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:168109024-168109744 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:168113086-168113654 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:168113655-168114223 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:168123500-168124015 Neighboring gene uncharacterized LOC107986547 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:168167604-168168104 Neighboring gene serine palmitoyltransferase long chain base subunit 2 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Transcriptome analysis reveals differentially expressed lncRNAs between oral squamous cell carcinoma and healthy oral mucosa. Feng L, et al. Oncotarget, 2017 May 9. PMID 28415559, Free PMC Article
  2. Tumor Suppressor LINC02487 Inhibits Oral Squamous Cell Carcinoma Cell Migration and Invasion Through the USP17-SNAI1 Axis. Feng L, et al. Front Oncol, 2020. PMID 33194625, Free PMC Article
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Clone Names

  • MGC138195

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_117092.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL009178, AL356123
    Related
    ENST00000644320.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    167680691..167696289 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    169018289..169034192 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001025489.1: Suppressed sequence

    Description
    NM_001025489.1: This RefSeq was permanently suppressed because currently insufficient support exists for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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