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LOC440895 two pore channel 3 pseudogene [ Homo sapiens (human) ]

Gene ID: 440895, updated on 10-Oct-2023

Summary

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Gene symbol
LOC440895
Gene description
two pore channel 3 pseudogene
See related
Ensembl:ENSG00000290731
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in testis (RPKM 64.8), endometrium (RPKM 16.8) and 1 other tissue See more
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Genomic context

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Location:
2q13
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (109947690..109968574)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (110705267..110726151)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene LIMS3-LOC440895 readthrough Neighboring gene LIM zinc finger domain containing 3 Neighboring gene uncharacterized LOC105373547 Neighboring gene uncharacterized LOC124907865 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:110738405-110738906 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:110738907-110739406 Neighboring gene glycosylphosphatidylinositol anchor attachment 1 pseudogene 1 Neighboring gene long intergenic non-protein coding RNA 1123 Neighboring gene zinc finger and BTB domain containing 45 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Degeneration of an intracellular ion channel in the primate lineage by relaxation of selective constraints. Cai X, et al. Mol Biol Evol, 2010 Oct. PMID 20463046
  2. Calcium signaling via two-pore channels: local or global, that is the question. Zhu MX, et al. Am J Physiol Cell Physiol, 2010 Mar. PMID 20018950, Free PMC Article
  3. An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles. Brailoiu E, et al. J Biol Chem, 2010 Jan 29. PMID 19940116, Free PMC Article
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Readthrough LIMS3-LOC440895

Readthrough gene: LIMS3-LOC440895, Included gene: LIMS3

Clone Names

  • FLJ13238, DKFZp434E232

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_027142.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) omits an internal exon, compared to variant 1.
    Source sequence(s)
    AA936147, AK310464, BI560270
    Related
    ENST00000433786.1

  2. NR_027143.3 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AC013268

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    109947690..109968574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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