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PRKCQ-AS1 PRKCQ antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 439949, updated on 10-Oct-2023

Summary

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Official Symbol
PRKCQ-AS1provided by HGNC
Official Full Name
PRKCQ antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:44689
See related
Ensembl:ENSG00000237943 AllianceGenome:HGNC:44689
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in lymph node (RPKM 5.5), appendix (RPKM 3.6) and 18 other tissues See more
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Genomic context

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Location:
10p15.1
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (6580425..6585361)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (6580547..6585491)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (6622387..6627323)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902370 Neighboring gene NANOG hESC enhancer GRCh37_chr10:6452056-6452557 Neighboring gene protein kinase C theta Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_13978 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_14068 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_14123 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2968 Neighboring gene uncharacterized LOC107984202 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_14215 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2108 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2109 Neighboring gene Sharpr-MPRA regulatory region 12587 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:6671711-6672282 Neighboring gene long intergenic non-protein coding RNA 2648 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:6690794-6691459 Neighboring gene NANOG hESC enhancer GRCh37_chr10:6720092-6720593 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:6778731-6779930 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:6779977-6780522 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:6780523-6781066 Neighboring gene lncRNA in non-homologous end joining pathway 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Long noncoding RNA PRKCQ-AS1 promotes CRC cell proliferation and migration via modulating miR-1287-5p/YBX1 axis. Cui G, et al. J Cell Biochem, 2020 Oct. PMID 32619070
  2. Expression Signatures of Long Noncoding RNAs in Adolescent Idiopathic Scoliosis. Liu XY, et al. Biomed Res Int, 2015. PMID 26421281, Free PMC Article
  3. Large-scale concatenation cDNA sequencing. Yu W, et al. Genome Res, 1997 Apr. PMID 9110174, Free PMC Article
  4. A "double adaptor" method for improved shotgun library construction. Andersson B, et al. Anal Biochem, 1996 Apr 5. PMID 8619474
  5. SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity. Shi P, et al. J Immunol, 2020 Jul 1. PMID 32393512

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Long noncoding RNA PRKCQ-AS1 promotes CRC cell proliferation and migration via modulating miR-1287-5p/YBX1 axis.
    Title: Long noncoding RNA PRKCQ-AS1 promotes CRC cell proliferation and migration via modulating miR-1287-5p/YBX1 axis.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • ENST00000414894.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_036502.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AL158043, CN429636

  2. NR_036503.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AL158043, AY007155
    Related
    ENST00000663449.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    6580425..6585361
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    6580547..6585491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases
Research Materials