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Btg1b BTG anti-proliferation factor 1B [ Mus musculus (house mouse) ]

Gene ID: 436199, updated on 22-Mar-2024

Summary

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Official Symbol
Btg1bprovided by MGI
Official Full Name
BTG anti-proliferation factor 1Bprovided by MGI
Primary source
MGI:MGI:3588262
See related
Ensembl:ENSMUSG00000121800 AllianceGenome:MGI:3588262
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Btg1-ps1; 4930525M21Rik
Summary
Predicted to enable enzyme binding activity. Predicted to be involved in several processes, including positive regulation of angiogenesis; positive regulation of endothelial cell differentiation; and positive regulation of fibroblast apoptotic process. Predicted to be active in cytoplasm and nucleus. Orthologous to human BTG1 (BTG anti-proliferation factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 3.0) See more
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Genomic context

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See Btg1b in Genome Data Viewer
Location:
X A3.3; X 22.27 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (37102050..37107727, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (38013173..38018850, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene reproductive homeobox 11, pseudogene 1 Neighboring gene reproductive homeobox 11, pseudogene 2 Neighboring gene BTG anti-proliferation factor 1C Neighboring gene reproductive homeobox 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. In search of a function for the TIS21/PC3/BTG1/TOB family. Matsuda S, et al. FEBS Lett, 2001 May 25. PMID 11377414
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in negative regulation of cell population proliferation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
B cell translocation gene 1, anti-proliferative-like
Names
B cell translocation gene 1, anti-proliferative, pseudogene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001243943.2 → NP_001230872.1  B cell translocation gene 1, anti-proliferative-like

    See identical proteins and their annotated locations for NP_001230872.1

    Status: VALIDATED

    Source sequence(s)
    AL512346
    Consensus CDS
    CCDS57753.1
    UniProtKB/TrEMBL
    Q3V0S2
    Related
    ENSMUST00000248500.1
    Conserved Domains (1) summary
    pfam07742
    Location:1 → 113
    BTG; BTG family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    37102050..37107727 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006541512.2 → XP_006541575.1  B cell translocation gene 1, anti-proliferative-like isoform X1

    Conserved Domains (1) summary
    pfam07742
    Location:13 → 125
    BTG; BTG family

  2. XM_006541513.2 → XP_006541576.1  B cell translocation gene 1, anti-proliferative-like isoform X2

    See identical proteins and their annotated locations for XP_006541576.1

    UniProtKB/TrEMBL
    Q3V0S2
    Conserved Domains (1) summary
    pfam07742
    Location:1 → 113
    BTG; BTG family
Nucleotide Protein Strain
Heading Accession and Version

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