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Cibar2 CBY1 interacting BAR domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 436062, updated on 11-Apr-2024

Summary

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Official Symbol
Cibar2provided by MGI
Official Full Name
CBY1 interacting BAR domain containing 2provided by MGI
Primary source
MGI:MGI:3588213
See related
Ensembl:ENSMUSG00000042269 AllianceGenome:MGI:3588213
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam92b; 1700120B06Rik
Summary
Predicted to be involved in cilium assembly. Predicted to act upstream of or within cell projection organization. Located in ciliary basal body. Is expressed in lung. Orthologous to human CIBAR2 (CBY1 interacting BAR domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in ovary adult (RPKM 3.7), lung adult (RPKM 3.1) and 10 other tissues See more
Orthologs
human all
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Genomic context

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Location:
8 E1; 8 69.09 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (120893136..120904225, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (120166397..120177486, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A130014A01 gene Neighboring gene RIKEN cDNA 6430548M08 gene Neighboring gene STARR-positive B cell enhancer ABC_E3811 Neighboring gene STARR-positive B cell enhancer mm9_chr8:122701278-122701579 Neighboring gene STARR-positive B cell enhancer ABC_E5046 Neighboring gene RIKEN cDNA A330074K22 gene Neighboring gene STARR-positive B cell enhancer ABC_E10527 Neighboring gene genetic suppressor element 1, coiled-coil protein Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:122809115-122809356 Neighboring gene VISTA enhancer mm196 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:122831174-122831375 Neighboring gene STARR-seq mESC enhancer starr_22881 Neighboring gene predicted gene, 32968

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BAR Domain-Containing FAM92 Proteins Interact with Chibby1 To Facilitate Ciliogenesis. Li FQ, et al. Mol Cell Biol, 2016 Nov 1. PMID 27528616, Free PMC Article
  2. Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Stauber M, et al. Dev Biol, 2017 Mar 15. PMID 27914912
  3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell projection organization IEA
Inferred from Electronic Annotation
more info
  
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ciliary basal body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in ciliary transition zone IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CBY1-interacting BAR domain-containing protein 2
Names
family with sequence similarity 92, member B
protein FAM92B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033980.2 → NP_001029152.2  CBY1-interacting BAR domain-containing protein 2

    See identical proteins and their annotated locations for NP_001029152.2

    Status: VALIDATED

    Source sequence(s)
    AC163442, BC147233
    Consensus CDS
    CCDS22717.1
    UniProtKB/Swiss-Prot
    B2RVK4, Q3V2J0
    Related
    ENSMUSP00000038825.7, ENSMUST00000048786.13
    Conserved Domains (1) summary
    cd07598
    Location:6 → 216
    BAR_FAM92; The Bin/Amphiphysin/Rvs (BAR) domain of Family with sequence similarity 92 (FAM92)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    120893136..120904225 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248434.1 → XP_011246736.1  CBY1-interacting BAR domain-containing protein 2 isoform X4

    Conserved Domains (1) summary
    cl12013
    Location:1 → 76
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  2. XM_030243658.1 → XP_030099518.1  CBY1-interacting BAR domain-containing protein 2 isoform X3

    Conserved Domains (1) summary
    cl12013
    Location:8 → 80
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_011248429.1 → XP_011246731.1  CBY1-interacting BAR domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011246731.1

    Conserved Domains (1) summary
    cd07598
    Location:6 → 216
    BAR_FAM92; The Bin/Amphiphysin/Rvs (BAR) domain of Family with sequence similarity 92 (FAM92)

  4. XM_011248431.1 → XP_011246733.1  CBY1-interacting BAR domain-containing protein 2 isoform X2

    Conserved Domains (1) summary
    cd07598
    Location:1 → 203
    BAR_FAM92; The Bin/Amphiphysin/Rvs (BAR) domain of Family with sequence similarity 92 (FAM92)

  5. XM_030243659.1 → XP_030099519.1  CBY1-interacting BAR domain-containing protein 2 isoform X3

    Conserved Domains (1) summary
    cl12013
    Location:8 → 80
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3V2J0.2 GenPept UniProtKB/Swiss-Prot:Q3V2J0

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