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Lsmem2 leucine-rich single-pass membrane protein 2 [ Mus musculus (house mouse) ]

Gene ID: 434436, updated on 5-Mar-2024

Summary

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Official Symbol
Lsmem2provided by MGI
Official Full Name
leucine-rich single-pass membrane protein 2provided by MGI
Primary source
MGI:MGI:3612240
See related
Ensembl:ENSMUSG00000103409 AllianceGenome:MGI:3612240
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Orthologous to human LSMEM2 (leucine rich single-pass membrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in heart adult (RPKM 16.0), mammary gland adult (RPKM 4.1) and 11 other tissues See more
Orthologs
human all
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Genomic context

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Location:
9 F1; 9 58.28 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (107469825..107475189, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (107592626..107597990, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2304 Neighboring gene STARR-seq mESC enhancer starr_25176 Neighboring gene hyaluronoglucosaminidase 2 Neighboring gene hyaluronoglucosaminidase 1 Neighboring gene STARR-positive B cell enhancer ABC_E300 Neighboring gene N(alpha)-acetyltransferase 80, NatH catalytic subunit Neighboring gene hyaluronoglucosaminidase 3 Neighboring gene interferon-related developmental regulator 2 Neighboring gene STARR-positive B cell enhancer ABC_E11753 Neighboring gene sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B Neighboring gene STARR-positive B cell enhancer ABC_E8314 Neighboring gene G protein subunit alpha i2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:107527067-107527220 Neighboring gene STARR-seq mESC enhancer starr_25181 Neighboring gene predicted gene, 53518 Neighboring gene STARR-seq mESC enhancer starr_25182 Neighboring gene STARR-positive B cell enhancer ABC_E5103 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:107546963-107547072 Neighboring gene STARR-positive B cell enhancer ABC_E8315 Neighboring gene solute carrier family 38, member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
leucine-rich single-pass membrane protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370877.1 → NP_001357806.1  leucine-rich single-pass membrane protein 2

    Status: VALIDATED

    Source sequence(s)
    AL672219
    Consensus CDS
    CCDS90659.1
    UniProtKB/TrEMBL
    A0A571BE98
    Related
    ENSMUSP00000158647.2, ENSMUST00000238519.2
    Conserved Domains (1) summary
    pfam15833
    Location:1 → 148
    DUF4714; Domain of unknown function (DUF4714)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    107469825..107475189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030244443.1 → XP_030100303.1  leucine-rich single-pass membrane protein 2 isoform X2

    Related
    ENSMUST00000191791.3
    Conserved Domains (1) summary
    pfam15833
    Location:10 → 151
    DUF4714; Domain of unknown function (DUF4714)

  2. XM_030244442.1 → XP_030100302.1  leucine-rich single-pass membrane protein 2 isoform X1

    Conserved Domains (1) summary
    pfam15833
    Location:16 → 162
    DUF4714; Domain of unknown function (DUF4714)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001081244.1: Suppressed sequence

    Description
    NM_001081244.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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