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Prrt1b proline rich transmembrane protein 1B [ Mus musculus (house mouse) ]

Gene ID: 433415, updated on 5-Mar-2024

Summary

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Official Symbol
Prrt1bprovided by MGI
Official Full Name
proline rich transmembrane protein 1Bprovided by MGI
Primary source
MGI:MGI:3649917
See related
Ensembl:ENSMUSG00000079497 AllianceGenome:MGI:3649917
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dspd2; Gm13420
Summary
Predicted to be active in membrane. Orthologous to human PRRT1B (proline rich transmembrane protein 1B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in stomach adult (RPKM 5.9), kidney adult (RPKM 1.9) and 4 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 B; 2 20.54 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (29630993..29641739, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (29740981..29751726, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_04054 Neighboring gene predicted gene, 30761 Neighboring gene STARR-positive B cell enhancer ABC_E7802 Neighboring gene STARR-seq mESC enhancer starr_04055 Neighboring gene STARR-positive B cell enhancer ABC_E9194 Neighboring gene STARR-positive B cell enhancer ABC_E2607 Neighboring gene STARR-seq mESC enhancer starr_04057 Neighboring gene Rap guanine nucleotide exchange factor (GEF) 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:29526317-29526500 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:29529743-29529852 Neighboring gene STARR-seq mESC enhancer starr_04064 Neighboring gene STARR-positive B cell enhancer ABC_E9506 Neighboring gene STARR-positive B cell enhancer ABC_E2608 Neighboring gene STARR-seq mESC enhancer starr_04069 Neighboring gene STARR-seq mESC enhancer starr_04071 Neighboring gene predicted gene 13547 Neighboring gene TruB pseudouridine (psi) synthase family member 2 Neighboring gene STARR-seq mESC enhancer starr_04073 Neighboring gene coenzyme Q4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The dispanins: a novel gene family of ancient origin that contains 14 human members. Sällman Almén M, et al. PLoS One, 2012. PMID 22363774, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
proline rich transmembrane protein 1B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370923.1 → NP_001357852.1  proline rich transmembrane protein 1B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL845323
    Consensus CDS
    CCDS89460.1
    UniProtKB/TrEMBL
    A0A140LJJ2
    Related
    ENSMUSP00000147234.2, ENSMUST00000129574.3
    Conserved Domains (2) summary
    PTZ00449
    Location:17 → 172
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam04505
    Location:171 → 237
    CD225; Interferon-induced transmembrane protein

  2. NM_001370924.1 → NP_001357853.1  proline rich transmembrane protein 1B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL845323
    Conserved Domains (1) summary
    pfam04505
    Location:171 → 199
    CD225; Interferon-induced transmembrane protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    29630993..29641739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006498497.2 → XP_006498560.1  proline rich transmembrane protein 1B isoform X1

    See identical proteins and their annotated locations for XP_006498560.1

    Conserved Domains (1) summary
    pfam04505
    Location:171 → 205
    CD225; Interferon-induced transmembrane protein
Nucleotide Protein
Heading Accession and Version

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