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Kbtbd6 kelch repeat and BTB (POZ) domain containing 6 [ Mus musculus (house mouse) ]

Gene ID: 432879, updated on 8-Feb-2024

Summary

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Official Symbol
Kbtbd6provided by MGI
Official Full Name
kelch repeat and BTB (POZ) domain containing 6provided by MGI
Primary source
MGI:MGI:3643058
See related
Ensembl:ENSMUSG00000075502 AllianceGenome:MGI:3643058
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm5465; Zbtbd6; EG432879
Summary
Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; and regulation of Rac protein signal transduction. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Cul3-RING ubiquitin ligase complex. Orthologous to human KBTBD6 (kelch repeat and BTB domain containing 6). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Kbtbd6 in Genome Data Viewer
Location:
14 D3; 14 42.66 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (79689275..79692256)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (79451835..79454816)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene N(alpha)-acetyltransferase 16, NatA auxiliary subunit Neighboring gene STARR-positive B cell enhancer ABC_E11576 Neighboring gene STARR-positive B cell enhancer ABC_E4121 Neighboring gene STARR-positive B cell enhancer ABC_E7342 Neighboring gene STARR-positive B cell enhancer ABC_E7343 Neighboring gene STARR-positive B cell enhancer ABC_E4122 Neighboring gene mitochondrial translational release factor 1 Neighboring gene kelch repeat and BTB (POZ) domain containing 7 Neighboring gene STARR-positive B cell enhancer ABC_E2429 Neighboring gene WW domain binding protein 4 Neighboring gene nuclear encoded tRNA glutamic acid 4 (anticodon TTC) Neighboring gene E74 like ETS transcription factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
  5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in protein K48-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of Rac protein signal transduction ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of Cul3-RING ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC432879

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034882.3 → NP_001030054.3  uncharacterized protein LOC432879

    Status: VALIDATED

    Source sequence(s)
    AC124745, AK159684
    Consensus CDS
    CCDS27299.2
    UniProtKB/TrEMBL
    A0A2I3BQ98, E9PYD7
    Related
    ENSMUSP00000154099.2, ENSMUST00000226192.2
    Conserved Domains (3) summary
    smart00225
    Location:64 → 168
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00875
    Location:173 → 274
    BACK; BTB And C-terminal Kelch
    pfam00651
    Location:53 → 164
    BTB; BTB/POZ domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    79689275..79692256
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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