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Actmap actin maturation protease [ Mus musculus (house mouse) ]

Gene ID: 414069, updated on 5-Mar-2024

Summary

Official Symbol
Actmapprovided by MGI
Official Full Name
actin maturation proteaseprovided by MGI
Primary source
MGI:MGI:3041247
See related
Ensembl:ENSMUSG00000078786 AllianceGenome:MGI:3041247
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Orthologous to human C19orf54 (chromosome 19 open reading frame 54). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 8.9), adrenal adult (RPKM 5.2) and 28 other tissues See more
Orthologs
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Genomic context

Location:
7 A3; 7 15.84 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (26894973..26909611)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (27195781..27210184)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancers ABC_E1725 and ABC_E288 Neighboring gene RAB4B, member RAS oncogene family Neighboring gene microRNA 3101 Neighboring gene MIA SH3 domain containing Neighboring gene STARR-positive B cell enhancer ABC_E3707 Neighboring gene small nuclear ribonucleoprotein polypeptide A Neighboring gene microRNA 1191 Neighboring gene inositol 1,4,5-trisphosphate 3-kinase C Neighboring gene STARR-positive B cell enhancer ABC_E2229 Neighboring gene coenzyme Q8B Neighboring gene STARR-positive B cell enhancer ABC_E4906 Neighboring gene numb-like Neighboring gene ribosomal protein L14 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables aminopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables cysteine-type aminopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables initiator methionyl aminopeptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables initiator methionyl aminopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in protein processing IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein processing ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
actin maturation protease
Names
UPF0692 protein C19orf54 homolog
actin aminopeptidase ACTMAP
NP_001230817.1
NP_001277440.1
NP_001277442.1
XP_017177823.1
XP_030098596.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001243888.1NP_001230817.1  actin maturation protease isoform 1

    See identical proteins and their annotated locations for NP_001230817.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC157561
    Consensus CDS
    CCDS57529.1
    UniProtKB/Swiss-Prot
    D3Z7G4, J3QPC3
    Related
    ENSMUSP00000137189.2, ENSMUST00000179391.8
  2. NM_001290511.1NP_001277440.1  actin maturation protease isoform 2

    See identical proteins and their annotated locations for NP_001277440.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice junction at the 5' end of the last exon compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC157561
    UniProtKB/TrEMBL
    F6XBP4
    Related
    ENSMUSP00000123290.2, ENSMUST00000155931.2
  3. NM_001290513.1NP_001277442.1  actin maturation protease isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC157561
    Consensus CDS
    CCDS71921.1
    UniProtKB/TrEMBL
    D3Z7G4
    Related
    ENSMUSP00000104016.2, ENSMUST00000108379.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    26894973..26909611
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242736.2XP_030098596.1  actin maturation protease isoform X1

  2. XM_017322334.3XP_017177823.1  actin maturation protease isoform X1

RNA

  1. XR_881742.4 RNA Sequence