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MAP4 microtubule associated protein 4 [ Homo sapiens (human) ]

Gene ID: 4134, updated on 7-Apr-2024

Summary

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Official Symbol
MAP4provided by HGNC
Official Full Name
microtubule associated protein 4provided by HGNC
Primary source
HGNC:HGNC:6862
See related
Ensembl:ENSG00000047849 MIM:157132; AllianceGenome:HGNC:6862
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Expression
Ubiquitous expression in heart (RPKM 53.7), brain (RPKM 28.3) and 23 other tissues See more
Orthologs
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Genomic context

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See MAP4 in Genome Data Viewer
Location:
3p21.31
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (47850695..48088848, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (47878026..48116148, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (47892185..48130338, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:47710070-47710273 Neighboring gene HIGD2A pseudogene 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19819 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14313 Neighboring gene Sharpr-MPRA regulatory region 56 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14315 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14316 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:47844773-47845298 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:47846226-47846422 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:47859072-47859572 Neighboring gene MPRA-validated peak4635 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14318 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:47879089-47879907 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:47883235-47883741 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:47888661-47888762 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:47893749-47894266 Neighboring gene DExH-box helicase 30 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:47912431-47912931 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19820 Neighboring gene microRNA 1226 Neighboring gene MPRA-validated peak4636 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14319 Neighboring gene VPS26B pseudogene 1 Neighboring gene MPRA-validated peak4637 silencer Neighboring gene ribosomal protein S27 pseudogene 30 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14321 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14322 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14320 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19821 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19822 Neighboring gene MPRA-validated peak4638 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48154883-48155384 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48155385-48155884 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:48157513-48158444 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48160097-48160597 Neighboring gene RNA, 7SL, cytoplasmic 664, pseudogene Neighboring gene ribosomal protein L17 pseudogene 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Structural insight into microtubule stabilization and kinesin inhibition by Tau family MAPs. Shigematsu H, et al. J Cell Biol, 2018 Dec 3. PMID 30275105, Free PMC Article
  2. Microtubule-Associated Protein 4 Is a Prognostic Factor and Promotes Tumor Progression in Lung Adenocarcinoma. Xia X, et al. Dis Markers, 2018. PMID 29743960, Free PMC Article
  3. Microtubule-associated protein-4 controls nanovesicle dynamics and T cell activation. Bustos-Morán E, et al. J Cell Sci, 2017 Apr 1. PMID 28209780, Free PMC Article
  4. Microtubule-associated protein 4 is an important regulator of cell invasion/migration and a potential therapeutic target in esophageal squamous cell carcinoma. Jiang YY, et al. Oncogene, 2016 Sep 15. PMID 26876215
  5. MAP4-dependent regulation of microtubule formation affects centrosome, cilia, and Golgi architecture as a central mechanism in growth regulation. Zahnleiter D, et al. Hum Mutat, 2015 Jan. PMID 25323976

See all (204) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MAP4 acts as an oncogene and prognostic marker and affects radioresistance by mediating epithelial-mesenchymal transition in lung adenocarcinoma.
    Title: MAP4 acts as an oncogene and prognostic marker and affects radioresistance by mediating epithelial-mesenchymal transition in lung adenocarcinoma.
  2. Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules' physical properties and neurite morphology.
    Title: Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules' physical properties and neurite morphology.
  3. Phosphatidylinositol-3-OH kinase signalling is spatially organized at endosomal compartments by microtubule-associated protein 4.
    Title: Phosphatidylinositol-3-OH kinase signalling is spatially organized at endosomal compartments by microtubule-associated protein 4.
  4. study reveals a molecular mechanism by which HPV16E7 perturbs host mitotic progression by interfering Mps1-MAP4 signaling cascade, which results in an extended infection window and may facilitate the persistent HPV16 infection
    Title: Human Papillomavirus 16 oncoprotein E7 retards mitotic progression by blocking Mps1-MAP4 signaling cascade.
  5. The strongest bond of MAP4 was found around the intertubulin-dimer interface such that MAP4 coexists on the microtubule with kinesin-1 bound to the intratubulin-dimer interface as well.
    Title: Structural insight into microtubule stabilization and kinesin inhibition by Tau family MAPs.
  6. Further experiments revealed that MAP4 regulates microtubule dynamics and promotes epidermal cell migration through Tctex-1. MAP4 and Tctex-1 play important roles in regulating the migration of epidermal cells under hypoxia.
    Title: MAP4 regulates Tctex-1 and promotes the migration of epidermal cells in hypoxia.
  7. Results suggest that Syk, MAP4, and calpain-1 expression are correlated with each other and these proteins may be involved in early stages of tumour spread.
    Title: Expression of Syk and MAP4 proteins in ovarian cancer.
  8. Expression level of MAP4 mRNA and protein in lung adenocarcinoma tissues were significantly higher than those in noncancerous tissues. MAP4 expression significantly correlated with tumor progression.
    Title: Microtubule-Associated Protein 4 Is a Prognostic Factor and Promotes Tumor Progression in Lung Adenocarcinoma.
  9. Microtubule-associated protein 4 (MAP4) controls the dynein-dependent transport of BTN3A1 in response to nucleic acid stimulation, thereby identifying MAP4 as an upstream regulator of BTN3A1. Thus, the depletion of either MAP4 or BTN3A1 impairs cytosolic DNA- or RNA-mediated type I IFN responses.
    Title: MAP4-regulated dynein-dependent trafficking of BTN3A1 controls the TBK1-IRF3 signaling axis.
  10. an intratumoral injection of MAP4-small interfering RNA (siRNA) remarkably inhibited the growth of the tumors that formed by the MAP4-expressing ESCC cells in nude mice, and a combination of MAP4-siRNA and Bevacizumab significantly enhanced the inhibition effect. Our data suggest that MAP4 is probably a useful prognostic biomarker and a potential therapeutic target for the disease.
    Title: Microtubule-associated protein 4 is an important regulator of cell invasion/migration and a potential therapeutic target in esophageal squamous cell carcinoma.
Submit: New GeneRIF Correction See all GeneRIFs (30)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

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Replication interactions

Interaction Pubs
Knockdown of microtubule-associated protein 4 (MAP4) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed
Knockdown of DNAL1 and MAP4 by siRNAs and shRNAs inhibits HIV-1 replication in HeLa P4.2 cells by blocking reverse transcription and 2-LTR formation PubMed
Knockdown of microtubule-associated protein 4 (MAP4) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

Protein interactions

Protein Gene Interaction Pubs
Pr55(Gag) gag Cellular biotinylated microtubule-associated protein 4 (MAP4) is incorporated into HIV-1 Gag virus-like particles PubMed
gag Interaction of HIV-1 Gag with microtubule-associated protein 4 (MAP4) is identified in a series of six affinity purification/mass spectrometry screens PubMed

Go to the HIV-1, Human Interaction Database

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC8617, DKFZp779A1753

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables microtubule stabilizing activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural molecule activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cilium disassembly IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within establishment of spindle orientation IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within establishment of spindle orientation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule cytoskeleton organization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in microtubule cytoskeleton organization ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in microtubule polymerization IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within microtubule sliding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within mitotic spindle organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of non-motile cilium assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in axon ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in axoneme IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
  
is_active_in microtubule IDA
Inferred from Direct Assay
more info
 PubMed 
part_of microtubule associated complex TAS
Traceable Author Statement
more info
 PubMed 
located_in microtubule cytoskeleton IDA
Inferred from Direct Assay
more info
  
located_in microtubule organizing center IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitotic spindle IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
  

General protein information

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Preferred Names
microtubule-associated protein 4
Names
MAP-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_052840.1 RefSeqGene

    Range
    77864..243585
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001134364.2 → NP_001127836.1  microtubule-associated protein 4 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks an alternate exon and uses an alternate splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 4) has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AA904866, AB209377, DA114613
    Consensus CDS
    CCDS46818.1
    UniProtKB/Swiss-Prot
    P27816
    Related
    ENSP00000379083.3, ENST00000395734.8
    Conserved Domains (1) summary
    pfam00418
    Location:992 → 1021
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  2. NM_001384675.1 → NP_001371604.1  microtubule-associated protein 4 isoform 92

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913 → 943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  3. NM_001384676.1 → NP_001371605.1  microtubule-associated protein 4 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:977 → 1007
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  4. NM_001384677.1 → NP_001371606.1  microtubule-associated protein 4 isoform 74

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:653 → 930
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:939 → 969
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  5. NM_001384678.1 → NP_001371607.1  microtubule-associated protein 4 isoform 55

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:587 → 931
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76 → 243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:966 → 996
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  6. NM_001384679.1 → NP_001371608.1  microtubule-associated protein 4 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:686 → 975
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:994 → 1024
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  7. NM_001384680.1 → NP_001371609.1  microtubule-associated protein 4 isoform 86

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:473 → 817
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:890 → 920
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  8. NM_001384681.1 → NP_001371610.1  microtubule-associated protein 4 isoform 56

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:951 → 981
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  9. NM_001384707.1 → NP_001371636.1  microtubule-associated protein 4 isoform 62

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 852
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:926 → 956
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  10. NM_001384729.1 → NP_001371658.1  microtubule-associated protein 4 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Consensus CDS
    CCDS33750.1
    UniProtKB/Swiss-Prot
    P27816, Q13082, Q59FT2, Q68D74, Q6ZUW9, Q86V26, Q96A76, Q96NS9
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:992 → 1022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  11. NM_001384730.1 → NP_001371659.1  microtubule-associated protein 4 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552 → 896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:969 → 999
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  12. NM_001384731.1 → NP_001371660.1  microtubule-associated protein 4 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592 → 936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:994 → 1024
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  13. NM_001384733.1 → NP_001371662.1  microtubule-associated protein 4 isoform 81

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:653 → 905
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:929 → 959
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  14. NM_001384734.1 → NP_001371663.1  microtubule-associated protein 4 isoform 40

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954 → 984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  15. NM_001384735.1 → NP_001371664.1  microtubule-associated protein 4 isoform 63

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954 → 984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  16. NM_001384736.1 → NP_001371665.1  microtubule-associated protein 4 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592 → 936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:1009 → 1039
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  17. NM_001384737.1 → NP_001371666.1  microtubule-associated protein 4 isoform 32

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 893
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:967 → 997
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  18. NM_001384738.1 → NP_001371667.1  microtubule-associated protein 4 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:587 → 931
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76 → 243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:1004 → 1034
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  19. NM_001384744.1 → NP_001371673.1  microtubule-associated protein 4 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:551 → 895
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:968 → 998
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  20. NM_001384745.1 → NP_001371674.1  microtubule-associated protein 4 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:699 → 948
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76 → 243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:1021 → 1051
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  21. NM_001384746.1 → NP_001371675.1  microtubule-associated protein 4 isoform 70

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:511 → 855
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913 → 943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  22. NM_001384748.1 → NP_001371677.1  microtubule-associated protein 4 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:587 → 931
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76 → 243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:1004 → 1034
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  23. NM_001384751.1 → NP_001371680.1  microtubule-associated protein 4 isoform 66

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:953 → 982
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  24. NM_001384752.1 → NP_001371681.1  microtubule-associated protein 4 isoform 106

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:575 → 852
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:721 → 995
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:882 → 912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  25. NM_001384753.1 → NP_001371682.1  microtubule-associated protein 4 isoform 87

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:589 → 885
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:888 → 918
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  26. NM_001384754.1 → NP_001371683.1  microtubule-associated protein 4 isoform 38

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:992 → 1022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  27. NM_001384755.1 → NP_001371684.1  microtubule-associated protein 4 isoform 94

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913 → 943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  28. NM_001384756.1 → NP_001371685.1  microtubule-associated protein 4 isoform 39

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:977 → 1007
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  29. NM_001384757.1 → NP_001371686.1  microtubule-associated protein 4 isoform 104

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:511 → 855
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:890 → 920
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  30. NM_001384758.1 → NP_001371687.1  microtubule-associated protein 4 isoform 100

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537 → 881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:901 → 931
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  31. NM_001384759.1 → NP_001371688.1  microtubule-associated protein 4 isoform 112

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:612 → 864
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:873 → 903
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  32. NM_001384760.1 → NP_001371689.1  microtubule-associated protein 4 isoform 120

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:534 → 811
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:680 → 954
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:841 → 871
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  33. NM_001384761.1 → NP_001371690.1  microtubule-associated protein 4 isoform 83

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:653 → 905
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:929 → 959
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  34. NM_001384762.1 → NP_001371691.1  microtubule-associated protein 4 isoform 127

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:197 → 511
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:546 → 576
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  35. NM_001384774.1 → NP_001371703.1  microtubule-associated protein 4 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:977 → 1007
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  36. NM_001384776.1 → NP_001371705.1  microtubule-associated protein 4 isoform

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537 → 881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:935 → 965
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  37. NM_001384777.1 → NP_001371706.1  microtubule-associated protein 4 isoform 52

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552 → 896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:969 → 999
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  38. NM_001384778.1 → NP_001371707.1  microtubule-associated protein 4 isoform 122

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:364 → 708
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:781 → 811
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  39. NM_001384779.1 → NP_001371708.1  microtubule-associated protein 4 isoform 69

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:679 → 917
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:920 → 950
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  40. NM_001384780.1 → NP_001371709.1  microtubule-associated protein 4 isoform 84

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:656 → 894
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:897 → 927
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  41. NM_001384781.1 → NP_001371710.1  microtubule-associated protein 4 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:992 → 1022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  42. NM_001384782.1 → NP_001371711.1  microtubule-associated protein 4 isoform 41

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552 → 896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954 → 984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  43. NM_001384783.1 → NP_001371712.1  microtubule-associated protein 4 isoform 80

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:630 → 907
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:931 → 961
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  44. NM_001384784.1 → NP_001371713.1  microtubule-associated protein 4 isoform 132

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:205 → 446
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:459 → 489
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  45. NM_001384785.1 → NP_001371714.1  microtubule-associated protein 4 isoform 116

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    pfam05109
    Location:665 → 980
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:867 → 897
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  46. NM_001384786.1 → NP_001371715.1  microtubule-associated protein 4 isoform 58

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552 → 896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:931 → 961
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  47. NM_001384787.1 → NP_001371716.1  microtubule-associated protein 4 isoform 117

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:552 → 829
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:698 → 972
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:859 → 889
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  48. NM_001384788.1 → NP_001371717.1  microtubule-associated protein 4 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592 → 936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:1009 → 1039
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  49. NM_001384789.1 → NP_001371718.1  microtubule-associated protein 4 isoform 119

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    pfam05109
    Location:641 → 956
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:843 → 873
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  50. NM_001384790.1 → NP_001371719.1  microtubule-associated protein 4 isoform 50

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592 → 936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:971 → 1001
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  51. NM_001384791.1 → NP_001371720.1  microtubule-associated protein 4 isoform 28

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:551 → 895
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:968 → 998
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  52. NM_001384792.1 → NP_001371721.1  microtubule-associated protein 4 isoform 49

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592 → 936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:971 → 1001
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  53. NM_001384793.1 → NP_001371722.1  microtubule-associated protein 4 isoform 105

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:629 → 881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:890 → 920
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  54. NM_001384794.1 → NP_001371723.1  microtubule-associated protein 4 isoform 82

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK13914
    Location:673 → 889
    PRK13914; invasion associated endopeptidase
    pfam00418
    Location:899 → 929
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  55. NM_001384795.1 → NP_001371724.1  microtubule-associated protein 4 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:604 → 948
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:93 → 260
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:1021 → 1051
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  56. NM_001384796.1 → NP_001371725.1  microtubule-associated protein 4 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592 → 936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:971 → 1001
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  57. NM_001384797.1 → NP_001371726.1  microtubule-associated protein 4 isoform 43

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:551 → 895
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:953 → 983
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  58. NM_001384798.1 → NP_001371727.1  microtubule-associated protein 4 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:992 → 1022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  59. NM_001384800.1 → NP_001371729.1  microtubule-associated protein 4 isoform 75

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:939 → 969
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  60. NM_001384802.1 → NP_001371731.1  microtubule-associated protein 4 isoform 128

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:180 → 429
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:502 → 532
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  61. NM_001384803.1 → NP_001371732.1  microtubule-associated protein 4 isoform 110

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:496 → 840
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:875 → 905
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  62. NM_001384804.1 → NP_001371733.1  microtubule-associated protein 4 isoform 73

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03307
    Location:532 → 910
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam00418
    Location:912 → 942
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  63. NM_001384805.1 → NP_001371734.1  microtubule-associated protein 4 isoform 121

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:534 → 811
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:680 → 954
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:841 → 871
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  64. NM_001384806.1 → NP_001371735.1  microtubule-associated protein 4 isoform 71

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913 → 943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  65. NM_001384807.1 → NP_001371736.1  microtubule-associated protein 4 isoform 111

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:496 → 840
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:875 → 905
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  66. NM_001384808.1 → NP_001371737.1  microtubule-associated protein 4 isoform 129

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:180 → 429
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:502 → 532
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  67. NM_001384809.1 → NP_001371738.1  microtubule-associated protein 4 isoform 108

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:575 → 852
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:721 → 995
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:882 → 912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  68. NM_001384810.1 → NP_001371739.1  microtubule-associated protein 4 isoform 65

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954 → 984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  69. NM_001384811.1 → NP_001371740.1  microtubule-associated protein 4 isoform 118

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:552 → 829
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:698 → 972
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:859 → 889
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  70. NM_001384812.1 → NP_001371741.1  microtubule-associated protein 4 isoform 133

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:180 → 429
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:449 → 479
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  71. NM_001384813.1 → NP_001371742.1  microtubule-associated protein 4 isoform 125

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:219 → 554
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:558 → 588
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  72. NM_001384814.1 → NP_001371743.1  microtubule-associated protein 4 isoform 44

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954 → 984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  73. NM_001384815.1 → NP_001371744.1  microtubule-associated protein 4 isoform 131

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:180 → 429
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:464 → 494
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  74. NM_001384816.1 → NP_001371745.1  microtubule-associated protein 4 isoform 27

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552 → 896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:969 → 999
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  75. NM_001384817.1 → NP_001371746.1  microtubule-associated protein 4 isoform 130

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:156 → 445
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:464 → 494
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  76. NM_001384819.1 → NP_001371748.1  microtubule-associated protein 4 isoform 76

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954 → 984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  77. NM_001384820.1 → NP_001371749.1  microtubule-associated protein 4 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 893
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:967 → 997
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  78. NM_001384824.1 → NP_001371753.1  microtubule-associated protein 4 isoform 59

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:653 → 905
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:929 → 959
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  79. NM_001384825.1 → NP_001371754.1  microtubule-associated protein 4 isoform 88

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537 → 881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:916 → 946
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  80. NM_001384826.1 → NP_001371755.1  microtubule-associated protein 4 isoform 113

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:606 → 817
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:841 → 871
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  81. NM_001384827.1 → NP_001371756.1  microtubule-associated protein 4 isoform 79

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:653 → 906
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:930 → 960
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  82. NM_001384828.1 → NP_001371757.1  microtubule-associated protein 4 isoform 57

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552 → 896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:931 → 961
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  83. NM_001384831.1 → NP_001371760.1  microtubule-associated protein 4 isoform 77

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK13914
    Location:656 → 900
    PRK13914; invasion associated endopeptidase
    pfam00418
    Location:905 → 935
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  84. NM_001384832.1 → NP_001371761.1  microtubule-associated protein 4 isoform 45

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537 → 881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954 → 984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  85. NM_001384834.1 → NP_001371763.1  microtubule-associated protein 4 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:545 → 889
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:962 → 992
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  86. NM_001384835.1 → NP_001371764.1  microtubule-associated protein 4 isoform 134

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:166 → 368
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:392 → 422
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  87. NM_001384836.1 → NP_001371765.1  microtubule-associated protein 4 isoform 48

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:951 → 981
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  88. NM_001384837.1 → NP_001371766.1  microtubule-associated protein 4 isoform 54

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:936 → 966
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  89. NM_001384838.1 → NP_001371767.1  microtubule-associated protein 4 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 910
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:983 → 1013
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  90. NM_001384839.1 → NP_001371768.1  microtubule-associated protein 4 isoform 89

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:468 → 812
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:885 → 915
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  91. NM_001384840.1 → NP_001371769.1  microtubule-associated protein 4 isoform 95

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:647 → 858
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:882 → 912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  92. NM_001384841.1 → NP_001371770.1  microtubule-associated protein 4 isoform 102

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537 → 881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:901 → 931
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  93. NM_001384842.1 → NP_001371771.1  microtubule-associated protein 4 isoform 114

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:600 → 838
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:841 → 871
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  94. NM_001384843.1 → NP_001371772.1  microtubule-associated protein 4 isoform 72

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:496 → 840
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913 → 943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  95. NM_001384844.1 → NP_001371773.1  microtubule-associated protein 4 isoform 109

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:575 → 852
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:721 → 995
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:882 → 912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  96. NM_001384845.1 → NP_001371774.1  microtubule-associated protein 4 isoform 101

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:468 → 812
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:870 → 900
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  97. NM_001384846.1 → NP_001371775.1  microtubule-associated protein 4 isoform 51

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:939 → 969
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  98. NM_001384847.1 → NP_001371776.1  microtubule-associated protein 4 isoform 67

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:679 → 917
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:920 → 950
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  99. NM_001384848.1 → NP_001371777.1  microtubule-associated protein 4 isoform 65

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954 → 984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  100. NM_001384849.1 → NP_001371778.1  microtubule-associated protein 4 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:562 → 906
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:979 → 1009
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  101. NM_001384850.1 → NP_001371779.1  microtubule-associated protein 4 isoform 61

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 852
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:926 → 956
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  102. NM_001384851.1 → NP_001371780.1  microtubule-associated protein 4 isoform 97

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:641 → 879
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:882 → 912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  103. NM_001384853.1 → NP_001371782.1  microtubule-associated protein 4 isoform 85

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:898 → 928
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  104. NM_001384856.1 → NP_001371785.1  microtubule-associated protein 4 isoform 124

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:364 → 708
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:743 → 773
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  105. NM_001384857.1 → NP_001371786.1  microtubule-associated protein 4 isoform 90

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552 → 896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:916 → 946
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  106. NM_001384859.1 → NP_001371788.1  microtubule-associated protein 4 isoform 98

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:549 → 893
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913 → 943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  107. NM_001384861.1 → NP_001371790.1  microtubule-associated protein 4 isoform 115

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    pfam05109
    Location:665 → 980
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:867 → 897
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  108. NM_001384862.1 → NP_001371791.1  microtubule-associated protein 4 isoform 123

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:505 → 757
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:781 → 811
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  109. NM_001384863.1 → NP_001371792.1  microtubule-associated protein 4 isoform 47

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:603 → 947
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:982 → 1012
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  110. NM_001384864.1 → NP_001371793.1  microtubule-associated protein 4 isoform 60

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:511 → 855
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:928 → 958
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  111. NM_001384866.1 → NP_001371795.1  microtubule-associated protein 4 isoform 99

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:638 → 876
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:879 → 909
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  112. NM_001384867.1 → NP_001371796.1  microtubule-associated protein 4 isoform 91

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:468 → 812
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:885 → 915
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  113. NM_001384868.1 → NP_001371797.1  microtubule-associated protein 4 isoform 46

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:951 → 981
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  114. NM_001384869.1 → NP_001371798.1  microtubule-associated protein 4 isoform 78

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552 → 896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:931 → 961
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  115. NM_001384870.1 → NP_001371799.1  microtubule-associated protein 4 isoform 93

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:647 → 858
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:882 → 912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  116. NM_001384871.1 → NP_001371800.1  microtubule-associated protein 4 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 894
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:968 → 998
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  117. NM_001384872.1 → NP_001371801.1  microtubule-associated protein 4 isoform 68

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:665 → 942
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76 → 243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:951 → 981
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  118. NM_001384873.1 → NP_001371802.1  microtubule-associated protein 4 isoform 33

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:549 → 893
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:966 → 996
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  119. NM_001384874.1 → NP_001371803.1  microtubule-associated protein 4 isoform 64

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:545 → 889
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:924 → 954
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  120. NM_001384875.1 → NP_001371804.1  microtubule-associated protein 4 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:587 → 931
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76 → 243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:989 → 1019
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  121. NM_001384876.1 → NP_001371805.1  microtubule-associated protein 4 isoform 42

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537 → 881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954 → 984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  122. NM_001384877.1 → NP_001371806.1  microtubule-associated protein 4 isoform 126

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:198 → 470
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:543 → 573
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  123. NM_001384878.1 → NP_001371807.1  microtubule-associated protein 4 isoform 96

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:572 → 878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913 → 943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  124. NM_001384879.1 → NP_001371808.1  microtubule-associated protein 4 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:992 → 1022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  125. NM_001384892.1 → NP_001371821.1  microtubule-associated protein 4 isoform 37

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:545 → 889
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:962 → 992
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  126. NM_001384893.1 → NP_001371822.1  microtubule-associated protein 4 isoform 103

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534 → 878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:898 → 928
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  127. NM_001385664.1 → NP_001372593.1  microtubule-associated protein 4 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:1775 → 2024
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:2059 → 2089
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  128. NM_001385665.1 → NP_001372594.1  microtubule-associated protein 4 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:992 → 1022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  129. NM_001385675.1 → NP_001372604.1  microtubule-associated protein 4 isoform 34

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:587 → 931
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76 → 243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:966 → 996
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  130. NM_001385676.1 → NP_001372605.1  microtubule-associated protein 4 isoform 107

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:615 → 853
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:856 → 886
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  131. NM_001385677.1 → NP_001372606.1  microtubule-associated protein 4 isoform 44

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954 → 984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  132. NM_001385681.1 → NP_001372610.1  microtubule-associated protein 4 isoform 25

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592 → 936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:971 → 1001
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  133. NM_001385682.1 → NP_001372611.1  microtubule-associated protein 4 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Consensus CDS
    CCDS93263.1
    UniProtKB/TrEMBL
    A0A804HKE7
    Related
    ENSP00000507895.1, ENST00000683076.1
    Conserved Domains (2) summary
    PHA03247
    Location:1815 → 2064
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:2137 → 2167
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  134. NM_001385684.1 → NP_001372613.1  microtubule-associated protein 4 isoform 53

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:939 → 969
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  135. NM_001385685.1 → NP_001372614.1  microtubule-associated protein 4 isoform 69

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:679 → 917
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:920 → 950
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  136. NM_001385686.1 → NP_001372615.1  microtubule-associated protein 4 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592 → 936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:1009 → 1039
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  137. NM_001385687.1 → NP_001372616.1  microtubule-associated protein 4 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:1815 → 2064
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:2137 → 2167
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  138. NM_001385688.1 → NP_001372617.1  microtubule-associated protein 4 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:1814 → 2051
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:2060 → 2090
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  139. NM_001385689.1 → NP_001372618.1  microtubule-associated protein 4 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:1815 → 2064
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:2099 → 2129
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  140. NM_001385690.1 → NP_001372619.1  microtubule-associated protein 4 isoform 135

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    UniProtKB/TrEMBL
    A0A0J9YW37

  141. NM_001385691.1 → NP_001372620.1  microtubule-associated protein 4 isoform 135

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    UniProtKB/TrEMBL
    A0A0J9YW37

  142. NM_001385692.1 → NP_001372621.1  microtubule-associated protein 4 isoform 135

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    UniProtKB/TrEMBL
    A0A0J9YW37

  143. NM_002375.5 → NP_002366.2  microtubule-associated protein 4 isoform 1

    See identical proteins and their annotated locations for NP_002366.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. It encodes the longest isoform (1).
    Source sequence(s)
    AA904866, AB209377, DA114613, M64571
    Consensus CDS
    CCDS33750.1
    UniProtKB/Swiss-Prot
    P27816, Q13082, Q59FT2, Q68D74, Q6ZUW9, Q86V26, Q96A76, Q96NS9
    Related
    ENSP00000353375.6, ENST00000360240.10
    Conserved Domains (2) summary
    PHA03247
    Location:575 → 919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:992 → 1022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  144. NM_030885.4 → NP_112147.2  microtubule-associated protein 4 isoform 3

    See identical proteins and their annotated locations for NP_112147.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks multiple exons in the 3' region and uses an unique splice site at the 3' end-exon compared to variant 1. The resulting isoform (3) has a distinct and shorter C-terminus, as compared to isoform 1.
    Source sequence(s)
    AA206810, AI078534, BC051843, DA114613, DA150735
    Consensus CDS
    CCDS46821.1
    UniProtKB/Swiss-Prot
    P27816
    Related
    ENSP00000397414.1, ENST00000439356.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    47850695..48088848 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047448133.1 → XP_047304089.1  microtubule-associated protein 4 isoform X23

  2. XM_047448129.1 → XP_047304085.1  microtubule-associated protein 4 isoform X18

  3. XM_047448128.1 → XP_047304084.1  microtubule-associated protein 4 isoform X17

  4. XM_047448125.1 → XP_047304081.1  microtubule-associated protein 4 isoform X14

  5. XM_047448119.1 → XP_047304075.1  microtubule-associated protein 4 isoform X7

  6. XM_047448132.1 → XP_047304088.1  microtubule-associated protein 4 isoform X22

  7. XM_047448127.1 → XP_047304083.1  microtubule-associated protein 4 isoform X16

  8. XM_047448122.1 → XP_047304078.1  microtubule-associated protein 4 isoform X10

  9. XM_047448121.1 → XP_047304077.1  microtubule-associated protein 4 isoform X9

    UniProtKB/TrEMBL
    E7EVA0
    Related
    ENSP00000407602.2, ENST00000426837.6

  10. XM_047448118.1 → XP_047304074.1  microtubule-associated protein 4 isoform X3

  11. XM_047448124.1 → XP_047304080.1  microtubule-associated protein 4 isoform X13

  12. XM_017006397.2 → XP_016861886.1  microtubule-associated protein 4 isoform X21

  13. XM_047448131.1 → XP_047304087.1  microtubule-associated protein 4 isoform X20

  14. XM_047448130.1 → XP_047304086.1  microtubule-associated protein 4 isoform X19

  15. XM_047448123.1 → XP_047304079.1  microtubule-associated protein 4 isoform X12

  16. XM_011533708.3 → XP_011532010.1  microtubule-associated protein 4 isoform X11

    Conserved Domains (1) summary
    pfam00418
    Location:2134 → 2163
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  17. XM_047448126.1 → XP_047304082.1  microtubule-associated protein 4 isoform X15

  18. XM_047448120.1 → XP_047304076.1  microtubule-associated protein 4 isoform X8

  19. XM_011533705.2 → XP_011532007.1  microtubule-associated protein 4 isoform X6

    Conserved Domains (1) summary
    pfam00418
    Location:2149 → 2178
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  20. XM_017006391.2 → XP_016861880.1  microtubule-associated protein 4 isoform X5

  21. XM_011533704.3 → XP_011532006.1  microtubule-associated protein 4 isoform X4

    Conserved Domains (1) summary
    pfam00418
    Location:2151 → 2180
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  22. XM_011533703.3 → XP_011532005.1  microtubule-associated protein 4 isoform X2

    Conserved Domains (1) summary
    pfam00418
    Location:2166 → 2195
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  23. XM_024453523.2 → XP_024309291.1  microtubule-associated protein 4 isoform X1

    Conserved Domains (3) summary
    pfam00418
    Location:2197 → 2226
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl00062
    Location:93 → 260
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cl26464
    Location:1844 → 2093
    Atrophin-1; Atrophin-1 family

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    47878026..48116148 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054346540.1 → XP_054202515.1  microtubule-associated protein 4 isoform X23

  2. XM_054346535.1 → XP_054202510.1  microtubule-associated protein 4 isoform X18

  3. XM_054346534.1 → XP_054202509.1  microtubule-associated protein 4 isoform X17

  4. XM_054346531.1 → XP_054202506.1  microtubule-associated protein 4 isoform X14

  5. XM_054346524.1 → XP_054202499.1  microtubule-associated protein 4 isoform X7

  6. XM_054346539.1 → XP_054202514.1  microtubule-associated protein 4 isoform X22

  7. XM_054346533.1 → XP_054202508.1  microtubule-associated protein 4 isoform X16

  8. XM_054346527.1 → XP_054202502.1  microtubule-associated protein 4 isoform X10

  9. XM_054346526.1 → XP_054202501.1  microtubule-associated protein 4 isoform X9

  10. XM_054346520.1 → XP_054202495.1  microtubule-associated protein 4 isoform X3

  11. XM_054346530.1 → XP_054202505.1  microtubule-associated protein 4 isoform X13

  12. XM_054346538.1 → XP_054202513.1  microtubule-associated protein 4 isoform X21

  13. XM_054346537.1 → XP_054202512.1  microtubule-associated protein 4 isoform X20

  14. XM_054346536.1 → XP_054202511.1  microtubule-associated protein 4 isoform X19

  15. XM_054346529.1 → XP_054202504.1  microtubule-associated protein 4 isoform X12

  16. XM_054346528.1 → XP_054202503.1  microtubule-associated protein 4 isoform X11

  17. XM_054346532.1 → XP_054202507.1  microtubule-associated protein 4 isoform X15

  18. XM_054346525.1 → XP_054202500.1  microtubule-associated protein 4 isoform X8

  19. XM_054346523.1 → XP_054202498.1  microtubule-associated protein 4 isoform X6

  20. XM_054346522.1 → XP_054202497.1  microtubule-associated protein 4 isoform X5

  21. XM_054346521.1 → XP_054202496.1  microtubule-associated protein 4 isoform X4

  22. XM_054346519.1 → XP_054202494.1  microtubule-associated protein 4 isoform X2

  23. XM_054346518.1 → XP_054202493.1  microtubule-associated protein 4 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001134365.1: Suppressed sequence

    Description
    NM_001134365.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

  2. NM_030884.3: Suppressed sequence

    Description
    NM_030884.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P27816.3 GenPept UniProtKB/Swiss-Prot:P27816

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