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LINC01121 long intergenic non-protein coding RNA 1121 [ Homo sapiens (human) ]

Gene ID: 400952, updated on 10-Oct-2023

Summary

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Official Symbol
LINC01121provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 1121provided by HGNC
Primary source
HGNC:HGNC:49266
See related
Ensembl:ENSG00000205054 AllianceGenome:HGNC:49266
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UNQ6975
Expression
Low expression observed in reference dataset See more
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Genomic context

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See LINC01121 in Genome Data Viewer
Location:
2p21
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (45174341..45254941, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (45179561..45260151, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (45401480..45482080, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45232925-45233468 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45233469-45234012 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45235286-45236059 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45237064-45237663 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45239927-45240747 Neighboring gene NANOG hESC enhancer GRCh37_chr2:45261729-45262230 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:45266703-45267902 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45291852-45292470 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45298897-45299398 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45299399-45299898 Neighboring gene SIX homeobox 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45303064-45303728 Neighboring gene uncharacterized LOC107985809 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45396231-45396731 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45397597-45398226 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45417644-45418148 Neighboring gene uncharacterized LOC105374576 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45446124-45447052 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45447053-45447979 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45483718-45484291 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:45484292-45484864 Neighboring gene uncharacterized LOC105374577 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45570374-45571192 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:45571193-45572010 Neighboring gene Sharpr-MPRA regulatory region 15185 Neighboring gene S1 RNA binding domain 1 Neighboring gene NANOG hESC enhancer GRCh37_chr2:45693107-45693617 Neighboring gene Sharpr-MPRA regulatory region 7031 Neighboring gene RNA, 7SL, cytoplasmic 414, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LINC01121 induced intervertebral disc degeneration via modulating miR-150-5p/MMP16 axis. Chen X, et al. J Gene Med, 2020 Oct. PMID 32436632
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Clark HF, et al. Genome Res, 2003 Oct. PMID 12975309, Free PMC Article
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LINC01121 induced intervertebral disc degeneration via modulating miR-150-5p/MMP16 axis.
    Title: LINC01121 induced intervertebral disc degeneration via modulating miR-150-5p/MMP16 axis.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • NGNL6975

Clone Names

  • FLJ38231

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_033831.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AW291903, AY358255
    Related
    ENST00000378479.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    45174341..45254941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    45179561..45260151 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
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