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kud kuduk [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39882, updated on 4-Apr-2024

Summary

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Official Symbol
kudprovided by FlyBase
Official Full Name
kudukprovided by FlyBase
Primary source
FLYBASE:FBgn0036667
Locus tag
Dmel_CG9669
See related
AllianceGenome:FB:FBgn0036667
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9669; Dmel\CG9669; Kud
Summary
Predicted to be involved in protein N-linked glycosylation. Is integral component of nuclear outer membrane. Orthologous to human TMEM258 (transmembrane protein 258). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
73D1-73D1; 3-45 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16844568..16844991, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16837668..16838091, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene nudC Neighboring gene uncharacterized protein Neighboring gene Tumor susceptibility gene 101 Neighboring gene uncharacterized protein Neighboring gene Zinc finger CCHC-type containing 7 Neighboring gene Rhodopsin 4 Neighboring gene seven in absentia

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture. Ding ZY, et al. J Cell Biol, 2017 Sep 4. PMID 28716842, Free PMC Article
  2. Many P-element insertions affect wing shape in Drosophila melanogaster. Weber K, et al. Genetics, 2005 Mar. PMID 15545659, Free PMC Article
  3. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. den Hoed M, et al. Nat Genet, 2013 Jun. PMID 23583979, Free PMC Article
  4. Comparative transcriptional analysis uncovers molecular processes in early and mature somatic cyst cells of Drosophila testes. Adashev VE, et al. Eur J Cell Biol, 2022 Jun-Aug. PMID 35667338
  5. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Li H, et al. DNA Res, 2016 Dec. PMID 27559081, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in nuclear envelope organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nuclear migration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein N-linked glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear outer membrane IDA
Inferred from Direct Assay
more info
 PubMed 
part_of oligosaccharyltransferase I complex IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
kuduk
Names
CG9669-PA
CG9669-PB
kud-PA
kud-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    16844568..16844991 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259878.1 → NP_001246807.1  kuduk, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246807.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VVA8
    UniProtKB/TrEMBL
    G2J5U1, Q6NP26
    Conserved Domains (1) summary
    pfam05251
    Location:5 → 78
    Ost5; Oligosaccharyltransferase subunit 5

  2. NM_140668.3 → NP_648925.1  kuduk, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648925.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VVA8
    UniProtKB/TrEMBL
    G2J5U1, Q6NP26
    Related
    FBpp0075098
    Conserved Domains (1) summary
    pfam05251
    Location:5 → 78
    Ost5; Oligosaccharyltransferase subunit 5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
G2J5U1 G2J5U1
Q9VVA8.1 Q9VVA8

Gene LinkOut

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