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CG7768 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39573, updated on 10-May-2024

Summary

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Official Symbol
CG7768provided by FlyBase
Primary source
FLYBASE:FBgn0036415
Locus tag
Dmel_CG7768
See related
AllianceGenome:FB:FBgn0036415
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7768
Summary
Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein peptidyl-prolyl isomerization. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Orthologous to human PPIF (peptidylprolyl isomerase F). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
70D4-70D4; 3-42 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (14218204..14218974)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (14211304..14212074)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene nanchung Neighboring gene nuclear fallout Neighboring gene saturn Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Quality of regulatory elements in Drosophila retrogenes. Bai Y, et al. Genomics, 2009 Jan. PMID 18848618, Free PMC Article
  2. Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics - An AI-Enabled Biological Target Discovery Platform. Pun FW, et al. Front Aging Neurosci, 2022. PMID 35837482, Free PMC Article
  3. Retroposed new genes out of the X in Drosophila. Betrán E, et al. Genome Res, 2002 Dec. PMID 12466289, Free PMC Article
  4. Conserved properties of Drosophila and human spermatozoal mRNA repertoires. Fischer BE, et al. Proc Biol Sci, 2012 Jul 7. PMID 22378807, Free PMC Article
  5. Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila. Bai Y, et al. Genome Biol, 2007. PMID 17233920, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cyclosporin A binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptidyl-prolyl cis-trans isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptidyl-prolyl cis-trans isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
  
involved_in protein peptidyl-prolyl isomerization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7768-PA
CG7768-PB
NP_648697.1
NP_729966.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    14218204..14218974
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168584.4 → NP_729966.1  uncharacterized protein Dmel_CG7768, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729966.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5U0U2, Q7K2I4
    Related
    FBpp0075479
    Conserved Domains (1) summary
    cd01926
    Location:4 → 162
    cyclophilin_ABH_like; cyclophilin_ABH_like: Cyclophilin A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which ...

  2. NM_140440.3 → NP_648697.1  uncharacterized protein Dmel_CG7768, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648697.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5U0U2, Q7K2I4
    Related
    FBpp0075478
    Conserved Domains (1) summary
    cd01926
    Location:4 → 162
    cyclophilin_ABH_like; cyclophilin_ABH_like: Cyclophilin A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K2I4 Q7K2I4

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