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CG18180 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39125, updated on 4-Apr-2024

Summary

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Official Symbol
CG18180provided by FlyBase
Primary source
FLYBASE:FBgn0036024
Locus tag
Dmel_CG18180
See related
AllianceGenome:FB:FBgn0036024
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG18180; SP151
Summary
Enables serine hydrolase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
67C3-67C3; 3-31 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9641013..9641913)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9634113..9635013)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene furry Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene CNMamide Receptor Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pathogen Virulence Impedes Mutualist-Mediated Enhancement of Host Juvenile Growth via Inhibition of Protein Digestion. Erkosar B, et al. Cell Host Microbe, 2015 Oct 14. PMID 26439865, Free PMC Article
  2. D-Alanylation of teichoic acids contributes to Lactobacillus plantarum-mediated Drosophila growth during chronic undernutrition. Matos RC, et al. Nat Microbiol, 2017 Dec. PMID 28993620, Free PMC Article
  3. The furry gene of Drosophila is important for maintaining the integrity of cellular extensions during morphogenesis. Cong J, et al. Development, 2001 Jul. PMID 11526084
  4. Sex-specific effects of cis-regulatory variants in Drosophila melanogaster. Coolon JD, et al. Genetics, 2013 Dec. PMID 24097411, Free PMC Article
  5. Effect of Low Doses (5-40 cGy) of Gamma-irradiation on Lifespan and Stress-related Genes Expression Profile in Drosophila melanogaster. Zhikrevetskaya S, et al. PLoS One, 2015. PMID 26248317, Free PMC Article

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine hydrolase activity HDA PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG18180-PA
NP_648341.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    9641013..9641913
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140084.2 → NP_648341.1  uncharacterized protein Dmel_CG18180 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648341.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H0RNA2, Q9VT25
    Related
    FBpp0076118
    Conserved Domains (2) summary
    smart00020
    Location:35 → 256
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:36 → 259
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SY29 Q8SY29
Q9VT25 Q9VT25

Gene LinkOut

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