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C10orf143 chromosome 10 open reading frame 143 [ Homo sapiens (human) ]

Gene ID: 387723, updated on 3-Apr-2024

Summary

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Official Symbol
C10orf143provided by HGNC
Official Full Name
chromosome 10 open reading frame 143provided by HGNC
Primary source
HGNC:HGNC:48677
See related
Ensembl:ENSG00000237489 AllianceGenome:HGNC:48677
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LINC00959
Expression
Ubiquitous expression in thyroid (RPKM 1.2), prostate (RPKM 1.0) and 25 other tissues See more
Orthologs
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Genomic context

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See C10orf143 in Genome Data Viewer
Location:
10q26.3
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (130035125..130110830, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (130961816..131039821, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (131862160..131909094, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene microRNA 4297 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131664970-131665634 Neighboring gene EBF transcription factor 3 Neighboring gene EBF3 antisense RNA 1 Neighboring gene VISTA enhancer hs232 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131692870-131693478 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131694193-131695097 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131695098-131696001 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131725181-131725712 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131747356-131748190 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131756502-131757174 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131758519-131759190 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131762665-131763636 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131764672-131765292 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131766535-131767154 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:131769017-131769636 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131770277-131771162 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:131771163-131772046 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131811814-131812654 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131842637-131843136 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131847250-131848134 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131903776-131904291 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4205 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4206 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4207 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2941 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4208 Neighboring gene uncharacterized LOC102724883 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4209 Neighboring gene uncharacterized LOC124902560 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131919446-131919946 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:131919947-131920447 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_11122 Neighboring gene uncharacterized LOC105378561 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_11124 Neighboring gene CTAGE family member 7, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Homology

General protein information

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Preferred Names
uncharacterized protein C10orf143
Names
long intergenic non-protein coding RNA 959

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355042.2 → NP_001341971.1  uncharacterized protein C10orf143

    Status: VALIDATED

    Source sequence(s)
    AL139123
    Consensus CDS
    CCDS86157.1
    UniProtKB/Swiss-Prot
    A0A1B0GUT2
    Related
    ENSP00000490233.1, ENST00000637128.2

RNA

  1. NR_034125.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK094118, AL139123, AW135007, EU250747
    Related
    ENST00000647406.1

  2. NR_149170.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139123

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    130035125..130110830 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024448009.2 → XP_024303777.1  uncharacterized protein C10orf143 isoform X3

    UniProtKB/TrEMBL
    A0A2R8YF93
    Related
    ENSP00000496273.1, ENST00000643056.1

  2. XM_024448007.2 → XP_024303775.1  uncharacterized protein C10orf143 isoform X1

  3. XM_024448008.2 → XP_024303776.1  uncharacterized protein C10orf143 isoform X2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    130961816..131039821 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054365906.1 → XP_054221881.1  uncharacterized protein C10orf143 isoform X3

  2. XM_054365904.1 → XP_054221879.1  uncharacterized protein C10orf143 isoform X1

  3. XM_054365905.1 → XP_054221880.1  uncharacterized protein C10orf143 isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A1B0GUT2.1 GenPept UniProtKB/Swiss-Prot:A0A1B0GUT2

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases
Research Materials