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Tas2r140 taste receptor, type 2, member 140 [ Mus musculus (house mouse) ]

Gene ID: 387616, updated on 8-Feb-2024

Summary

Official Symbol
Tas2r140provided by MGI
Official Full Name
taste receptor, type 2, member 140provided by MGI
Primary source
MGI:MGI:2681298
See related
Ensembl:ENSMUSG00000071147 AllianceGenome:MGI:2681298
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TRB3; TRB5; T2R40; T2r34; mTRB3; Tas2r8; mt2r64; Tas2r13; Tas2r40; Tas2r137
Summary
Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of taste. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TAS2R14 (taste 2 receptor member 14). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See Tas2r140 in Genome Data Viewer
Location:
6 G1; 6 64.03 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (133031818..133032756, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (133054855..133055793, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene taste receptor, type 2, member 117 pseudogene Neighboring gene taste receptor, type 2, member 103 Neighboring gene predicted gene, 35765 Neighboring gene STARR-seq mESC enhancer starr_17519 Neighboring gene taste receptor, type 2, member 125 pseudogene

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables bitter taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables bitter taste receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables taste receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables taste receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
taste receptor type 2 member 140
Names
T2R13
T2R140
T2R8
mTRB5
taste receptor family B member 3
taste receptor type 2 member 40

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021562.1NP_067537.1  taste receptor type 2 member 140

    See identical proteins and their annotated locations for NP_067537.1

    Status: PROVISIONAL

    Source sequence(s)
    BK001092
    Consensus CDS
    CCDS20633.1
    UniProtKB/Swiss-Prot
    A6H6Q9, Q7TQA4, Q9JKA0, Q9JKA2
    Related
    ENSMUSP00000093040.3, ENSMUST00000095391.3
    Conserved Domains (1) summary
    pfam05296
    Location:1301
    TAS2R; Taste receptor protein (TAS2R)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    133031818..133032756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)