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LINC00320 long intergenic non-protein coding RNA 320 [ Homo sapiens (human) ]

Gene ID: 387486, updated on 10-Oct-2023

Summary

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Official Symbol
LINC00320provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 320provided by HGNC
Primary source
HGNC:HGNC:19690
See related
Ensembl:ENSG00000224924 AllianceGenome:HGNC:19690
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRED14; C21orf131; NCRNA00320
Expression
Restricted expression toward brain (RPKM 6.9) See more
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Genomic context

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Location:
21q21.1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (20742590..20803108, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (19104999..19165518, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (22114908..22175426, complement)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene RPS3A pseudogene 1 Neighboring gene MPRA-validated peak4373 silencer Neighboring gene NANOG hESC enhancer GRCh37_chr21:21943094-21943647 Neighboring gene MPRA-validated peak4374 silencer Neighboring gene MED14-independent group 3 enhancer GRCh37_chr21:21964409-21965608 Neighboring gene uncharacterized LOC124905064 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr21:22033338-22033876 Neighboring gene Sharpr-MPRA regulatory region 8374 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:22061254-22062453 Neighboring gene MPRA-validated peak4375 silencer Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr21:22162172-22162685 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr21:22162686-22163198 Neighboring gene MPRA-validated peak4376 silencer Neighboring gene peptidylprolyl isomerase A pseudogene 1 Neighboring gene uncharacterized LOC124905057

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Long non-coding RNA Linc00320 inhibits glioma cell proliferation through restraining Wnt/β-catenin signaling. Tian S, et al. Biochem Biophys Res Commun, 2019 Jan 8. PMID 30503496
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Clone Names

  • FLJ37539, DKFZp686B23275

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024090.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate 3' exon, compared to variant 1.
    Source sequence(s)
    AK094858, AP000957, BC042856, BC064598, BX537735
    Related
    ENST00000437238.6

  2. NR_109786.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    AK094858, AP000957, BC042856, BC047405, BC064598, BX537735
    Related
    ENST00000658703.1

  3. NR_109787.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate 5' exon and lacks multiple internal exons, compared to variant 1.
    Source sequence(s)
    AK094858, AP000957, BC042856, BC064598, BX537735
    Related
    ENST00000416768.6

  4. NR_109788.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate 5' exon and lacks multiple internal exons, compared to variant 1.
    Source sequence(s)
    AK094858, AP000957, BC042856, BC064598, BX537735
    Related
    ENST00000658084.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    20742590..20803108 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    19104999..19165518 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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