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Tas2r104 taste receptor, type 2, member 104 [ Mus musculus (house mouse) ]

Gene ID: 387340, updated on 11-Apr-2024

Summary

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Official Symbol
Tas2r104provided by MGI
Official Full Name
taste receptor, type 2, member 104provided by MGI
Primary source
MGI:MGI:2681185
See related
Ensembl:ENSMUSG00000061977 AllianceGenome:MGI:2681185
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
T2R04; mGR04; Tas2r4; mt2r45
Summary
Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TAS2R10 (taste 2 receptor member 10). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
6 F3; 6 63.53 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (131661799..131662707, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (131684836..131685744, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene taste receptor, type 2, member 107 Neighboring gene taste receptor, type 2, member 106 Neighboring gene taste receptor, type 2, member 105 Neighboring gene taste receptor, type 2, member 114

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Transcription Factor Etv1/Er81 Is Involved in the Differentiation of Sweet, Umami, and Sodium Taste Cells. Ohmoto M, et al. eNeuro, 2023 Apr. PMID 37045597, Free PMC Article
  2. T2Rs function as bitter taste receptors. Chandrashekar J, et al. Cell, 2000 Mar 17. PMID 10761935
  3. Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice. Nelson TM, et al. BMC Genet, 2005 Jun 6. PMID 15938754, Free PMC Article
  4. Evolutionary relationships of the Tas2r receptor gene families in mouse and human. Conte C, et al. Physiol Genomics, 2003 Jun 24. PMID 12734386
  5. Adaptive diversification of bitter taste receptor genes in Mammalian evolution. Shi P, et al. Mol Biol Evol, 2003 May. PMID 12679530

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables bitter taste receptor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in detection of chemical stimulus involved in sensory perception of bitter taste ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within response to stimulus IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sensory perception of taste IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of taste IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
taste receptor type 2 member 104
Names
T2R104

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207011.1 → NP_996894.1  taste receptor type 2 member 104

    See identical proteins and their annotated locations for NP_996894.1

    Status: PROVISIONAL

    Source sequence(s)
    BK001074
    Consensus CDS
    CCDS20611.1
    UniProtKB/Swiss-Prot
    A7MAX0, Q7M723
    Related
    ENSMUSP00000072237.3, ENSMUST00000072404.3
    Conserved Domains (1) summary
    cd15021
    Location:7 → 291
    7tm_TAS2R10; mammalian taste receptor 2, subtype 10, member of the seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    131661799..131662707 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7M723.1 GenPept UniProtKB/Swiss-Prot:Q7M723

Gene LinkOut

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