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SLC6A10P solute carrier family 6 member 10, pseudogene [ Homo sapiens (human) ]

Gene ID: 386757, updated on 10-Oct-2023

Summary

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Official Symbol
SLC6A10Pprovided by HGNC
Official Full Name
solute carrier family 6 member 10, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:11043
See related
Ensembl:ENSG00000290985 AllianceGenome:HGNC:11043
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT2; CT-2; SLC6A10; SLC6A10pA
Expression
Biased expression in testis (RPKM 15.1), adrenal (RPKM 2.0) and 1 other tissue See more
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Genomic context

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Location:
16p11.2
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (32877473..32885142, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (33399529..33407199)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (32888794..32896463, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene immunoglobulin heavy variable 2/OR16-5 (non-functional) Neighboring gene B cell receptor associated protein 31 pseudogene 2 Neighboring gene immunoglobulin heavy variable 3/OR16-15 (pseudogene) Neighboring gene immunoglobulin heavy variable 3/OR16-6 (pseudogene)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Assignment of the human creatine transporter type 2 (SLC6A10) to chromosome band 16p11.2 by in situ hybridization. Xu W, et al. Cytogenet Cell Genet, 1997. PMID 9154116
  2. Duplication of a gene-rich cluster between 16p11.1 and Xq28: a novel pericentromeric-directed mechanism for paralogous genome evolution. Eichler EE, et al. Hum Mol Genet, 1996 Jul. PMID 8817324
  3. Expression profile of COL2A1 and the pseudogene SLC6A10P predicts tumor recurrence in high-grade serous ovarian cancer. Ganapathi MK, et al. Int J Cancer, 2016 Feb 1. PMID 26311224
  4. Cloning and characterization of the promoter regions from the parent and paralogous creatine transporter genes. Ndika JD, et al. Gene, 2014 Jan 10. PMID 24144841
  5. Identification of a testis-expressed creatine transporter gene at 16p11.2 and confirmation of the X-linked locus to Xq28. Iyer GS, et al. Genomics, 1996 May 15. PMID 8661037

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. estimated median of 95 months as compared to an estimated median of 16 months for subjects expressing other levels of COL2A1 and SLC6A10P
    Title: Expression profile of COL2A1 and the pseudogene SLC6A10P predicts tumor recurrence in high-grade serous ovarian cancer.
  2. This is the first experimental evidence of a pseudogene (SLC6A10P) with stronger promoter activity than its parental gene (SLC6A8).
    Title: Cloning and characterization of the promoter regions from the parent and paralogous creatine transporter genes.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • creatine transporter-2
  • solute carrier family 6 (neurotransmitter transporter), member 10, pseudogene
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 10, pseudogene

Clone Names

  • FLJ43855

General protein information

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Preferred Names
similar to sodium- and chloride-dependent creatine transporter

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003083.3 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC142086
    Related
    ENST00000330048.9

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    32877473..32885142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    33399529..33407199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_198857.1: Suppressed sequence

    Description
    NM_198857.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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