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Ms4a14 membrane-spanning 4-domains, subfamily A, member 14 [ Mus musculus (house mouse) ]

Gene ID: 383435, updated on 18-Apr-2024

Summary

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Official Symbol
Ms4a14provided by MGI
Official Full Name
membrane-spanning 4-domains, subfamily A, member 14provided by MGI
Primary source
MGI:MGI:2686122
See related
Ensembl:ENSMUSG00000099398 AllianceGenome:MGI:2686122
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1276; SP3111
Summary
Orthologous to human MS4A14 (membrane spanning 4-domains A14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 68.4) See more
Orthologs
human all
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Genomic context

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Location:
19 A; 19 8.37 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (11278613..11293239, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (11301249..11315877, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930526L06 gene Neighboring gene STARR-positive B cell enhancer ABC_E3243 Neighboring gene membrane-spanning 4-domains, subfamily A, member 1 Neighboring gene STARR-seq mESC enhancer starr_45568 Neighboring gene membrane-spanning 4-domains, subfamily A, member 5 Neighboring gene STARR-seq mESC enhancer starr_45570 Neighboring gene membrane-spanning 4-domains, subfamily A, member 7 Neighboring gene membrane-spanning 4-domains, subfamily A, member 4A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. [Role of SP3111 protein in fertilization and early embryo development in mice]. Jia XF, et al. Zhonghua Nan Ke Xue, 2010 Jan. PMID 20180398
  2. Comparative analysis of testis protein evolution in rodents. Turner LM, et al. Genetics, 2008 Aug. PMID 18689890, Free PMC Article
  3. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1)  1 citation

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
membrane-spanning 4-domains subfamily A member 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001377045.1 → NP_001363974.1  membrane-spanning 4-domains subfamily A member 14

    Status: VALIDATED

    Source sequence(s)
    AC134839
    UniProtKB/TrEMBL
    A0A087WSD2
    Related
    ENSMUSP00000140996.2, ENSMUST00000187467.2
    Conserved Domains (3) summary
    PTZ00395
    Location:313 → 759
    PTZ00395; Sec24-related protein; Provisional
    PHA03378
    Location:520 → 710
    PHA03378; EBNA-3B; Provisional
    pfam04103
    Location:44 → 137
    CD20; CD20-like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    11278613..11293239 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247415.4 → XP_011245717.1  membrane-spanning 4-domains subfamily A member 14 isoform X1

    See identical proteins and their annotated locations for XP_011245717.1

    UniProtKB/TrEMBL
    A0A087WSD2
    Conserved Domains (3) summary
    PTZ00395
    Location:313 → 759
    PTZ00395; Sec24-related protein; Provisional
    PHA03378
    Location:520 → 710
    PHA03378; EBNA-3B; Provisional
    pfam04103
    Location:44 → 137
    CD20; CD20-like family

  2. XM_006527511.3 → XP_006527574.1  membrane-spanning 4-domains subfamily A member 14 isoform X3

    Conserved Domains (3) summary
    PTZ00395
    Location:280 → 726
    PTZ00395; Sec24-related protein; Provisional
    PHA03378
    Location:487 → 677
    PHA03378; EBNA-3B; Provisional
    pfam04103
    Location:44 → 137
    CD20; CD20-like family

  3. XM_006527510.3 → XP_006527573.1  membrane-spanning 4-domains subfamily A member 14 isoform X2

    Conserved Domains (3) summary
    PTZ00395
    Location:312 → 758
    PTZ00395; Sec24-related protein; Provisional
    PHA03378
    Location:519 → 709
    PHA03378; EBNA-3B; Provisional
    pfam04103
    Location:44 → 136
    CD20; CD20-like family
Nucleotide Protein
Heading Accession and Version

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