U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tvp23a trans-golgi network vesicle protein 23A [ Mus musculus (house mouse) ]

Gene ID: 383103, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Tvp23aprovided by MGI
Official Full Name
trans-golgi network vesicle protein 23Aprovided by MGI
Primary source
MGI:MGI:3665441
See related
Ensembl:ENSMUSG00000050908 AllianceGenome:MGI:3665441
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam18a
Summary
Predicted to be involved in protein secretion and vesicle-mediated transport. Predicted to be integral component of Golgi membrane. Orthologous to human TVP23A (trans-golgi network vesicle protein 23 homolog A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 13.8), CNS E18 (RPKM 13.4) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
16 A1; 16 5.61 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (10237397..10265251, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (10419533..10447390, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30724 Neighboring gene tektin 5 Neighboring gene predicted gene, 41419 Neighboring gene STARR-positive B cell enhancer ABC_E10886 Neighboring gene nucleotide binding protein 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:10469529-10469712 Neighboring gene STARR-seq mESC enhancer starr_40087 Neighboring gene predicted gene, 41420 Neighboring gene STARR-positive B cell enhancer mm9_chr16:10487992-10488292 Neighboring gene class II transactivator Neighboring gene predicted gene, 57630

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Evolution of mammalian chitinase(-like) members of family 18 glycosyl hydrolases. Bussink AP, et al. Genetics, 2007 Oct. PMID 17720922, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Golgi apparatus membrane protein TVP23 homolog A
Names
family with sequence similarity 18, member A

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013778.2 → NP_001013800.1  Golgi apparatus membrane protein TVP23 homolog A isoform 1

    See identical proteins and their annotated locations for NP_001013800.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC122352
    Consensus CDS
    CCDS27949.1
    UniProtKB/TrEMBL
    Q6NVH0
    Related
    ENSMUSP00000052922.7, ENSMUST00000051118.7
    Conserved Domains (1) summary
    pfam05832
    Location:39 → 180
    DUF846; Eukaryotic protein of unknown function (DUF846)

  2. NM_001359069.1 → NP_001345998.1  Golgi apparatus membrane protein TVP23 homolog A isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a alternate AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AC122352
    Conserved Domains (1) summary
    pfam05832
    Location:30 → 171
    DUF846; Eukaryotic protein of unknown function (DUF846)

  3. NM_001429122.1 → NP_001416051.1  Golgi apparatus membrane protein TVP23 homolog A isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC122352

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    10237397..10265251 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522315.5 → XP_006522378.1  Golgi apparatus membrane protein TVP23 homolog A isoform X2

    Conserved Domains (1) summary
    pfam05832
    Location:30 → 189
    DUF846; Eukaryotic protein of unknown function (DUF846)

  2. XM_006522314.5 → XP_006522377.1  Golgi apparatus membrane protein TVP23 homolog A isoform X1

    Conserved Domains (1) summary
    pfam05832
    Location:39 → 198
    DUF846; Eukaryotic protein of unknown function (DUF846)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous