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H2bc26 H2B clustered histone 26 [ Mus musculus (house mouse) ]

Gene ID: 382522, updated on 8-Feb-2024

Summary

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Official Symbol
H2bc26provided by MGI
Official Full Name
H2B clustered histone 26provided by MGI
Primary source
MGI:MGI:1922442
See related
Ensembl:ENSMUSG00000080712 AllianceGenome:MGI:1922442
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2bu1; H2bu1-ps; H2bc26-ps; Hist3h2bb; 4933432H21; B2Hist3h2bb; Hist3h2bb-ps; 4930534G10Rik
Summary
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2b family. [provided by RefSeq, Feb 2021]
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Genomic context

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See H2bc26 in Genome Data Viewer
Location:
11 B1.3; 11 36.38 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (58842961..58845278, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (58954048..58954512, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 187 Neighboring gene predicted gene, 51864 Neighboring gene STARR-positive B cell enhancer ABC_E3954 Neighboring gene H2B clustered histone 27 Neighboring gene STARR-positive B cell enhancer ABC_E114 Neighboring gene H2A clustered histone 25 Neighboring gene tripartite motif-containing 17 Neighboring gene STARR-positive B cell enhancer ABC_E5230 Neighboring gene STARR-positive B cell enhancer ABC_E6989 Neighboring gene H3.4 histone, cluster member

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Histone modifications associated with somatic hypermutation. Odegard VH, et al. Immunity, 2005 Jul. PMID 16039583
  2. Phosphorylation of histone H2B at DNA double-strand breaks. Fernandez-Capetillo O, et al. J Exp Med, 2004 Jun 21. PMID 15197225, Free PMC Article
  3. Gene mapping of sperm quality parameters in recombinant inbred strains of mice. Golas A, et al. Int J Dev Biol, 2008. PMID 18311719
  4. An expanded Oct4 interaction network: implications for stem cell biology, development, and disease. Pardo M, et al. Cell Stem Cell, 2010 Apr 2. PMID 20362542, Free PMC Article
  5. Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis. Cirilli M, et al. Biochim Biophys Acta Gen Subj, 2017 Feb. PMID 27746211

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Clone Names

  • MGC130256

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
histone H2B type 3-B
Names
H2B.U histone 1, pseudogene
histone 3, H2bb
histone cluster 3, H2bb, pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001393523.1 → NP_001380452.1  histone H2B type 3-B

    Status: VALIDATED

    Source sequence(s)
    AL662809
    UniProtKB/Swiss-Prot
    Q3B7Z7, Q8CGP0
    UniProtKB/TrEMBL
    A0JLV3
    Related
    ENSMUSP00001091675.1, ENSMUST00000117558.3
    Conserved Domains (1) summary
    smart00427
    Location:36 → 124
    H2B; Histone H2B

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    58842961..58845278 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_134309.1: Suppressed sequence

    Description
    NR_134309.1: This RefSeq was removed because it is now thought that this gene does encode a protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CGP0.3 GenPept UniProtKB/Swiss-Prot:Q8CGP0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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