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Cenatac centrosomal AT-AC splicing factor [ Mus musculus (house mouse) ]

Gene ID: 382073, updated on 5-Mar-2024

Summary

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Official Symbol
Cenatacprovided by MGI
Official Full Name
centrosomal AT-AC splicing factorprovided by MGI
Primary source
MGI:MGI:2685960
See related
Ensembl:ENSMUSG00000043923 AllianceGenome:MGI:2685960
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ccdc84; Gm1114; D630044F24Rik
Summary
Predicted to be involved in negative regulation of centrosome duplication and regulation of protein catabolic process. Predicted to be located in centrosome. Orthologous to human CENATAC (centrosomal AT-AC splicing factor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 9.6), CNS E14 (RPKM 9.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Cenatac in Genome Data Viewer
Location:
9 A5.2; 9 24.84 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (44321456..44329390, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (44410159..44418084, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 37 (glucose-6-phosphate transporter), member 4 Neighboring gene microRNA 7085 Neighboring gene STARR-positive B cell enhancer ABC_E2291 Neighboring gene trafficking protein particle complex 4 Neighboring gene ribosomal protein S25 Neighboring gene STARR-seq mESC enhancer starr_23968 Neighboring gene forkhead box R1 Neighboring gene uroplakin 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC106805

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
  
involved_in chromosome separation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of centrosome duplication ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of protein catabolic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
centrosomal AT-AC splicing factor
Names
coiled-coil domain containing 84
coiled-coil domain-containing protein 84

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201372.4 → NP_958760.2  centrosomal AT-AC splicing factor

    See identical proteins and their annotated locations for NP_958760.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the protein-coding transcript.
    Source sequence(s)
    AC122428
    Consensus CDS
    CCDS23110.1
    UniProtKB/Swiss-Prot
    Q3TAL6, Q4VA36, Q7TNQ4, Q8C702
    Related
    ENSMUSP00000053216.8, ENSMUST00000053286.9
    Conserved Domains (1) summary
    pfam14968
    Location:7 → 320
    CCDC84; Coiled coil protein 84

RNA

  1. NR_151775.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice junction compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC122428, AK052757

  2. NR_151776.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice junction compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC122428
    Related
    ENSMUST00000214494.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    44321456..44329390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006510472.4 → XP_006510535.1  centrosomal AT-AC splicing factor isoform X1

    Conserved Domains (1) summary
    pfam14968
    Location:7 → 329
    CCDC84; Coiled coil protein 84

  2. XM_036155094.1 → XP_036010987.1  centrosomal AT-AC splicing factor isoform X2

    Conserved Domains (1) summary
    pfam14968
    Location:7 → 246
    CCDC84; Coiled coil protein 84

RNA

  1. XR_004935474.1 RNA Sequence

  2. XR_004935471.1 RNA Sequence

  3. XR_004935470.1 RNA Sequence

  4. XR_003947942.2 RNA Sequence

  5. XR_004935476.1 RNA Sequence

  6. XR_004935475.1 RNA Sequence

  7. XR_004935473.1 RNA Sequence

  8. XR_003947941.2 RNA Sequence

  9. XR_003947940.2 RNA Sequence

  10. XR_001778937.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4VA36.1 GenPept UniProtKB/Swiss-Prot:Q4VA36

Gene LinkOut

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