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Cep44 centrosomal protein 44 [ Mus musculus (house mouse) ]

Gene ID: 382010, updated on 5-Mar-2024

Summary

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Official Symbol
Cep44provided by MGI
Official Full Name
centrosomal protein 44provided by MGI
Primary source
MGI:MGI:3525111
See related
Ensembl:ENSMUSG00000038215 AllianceGenome:MGI:3525111
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1712; 4933440G23Rik
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in centriole replication and centriole-centriole cohesion. Predicted to be located in centriole. Predicted to be active in centrosome and spindle pole. Orthologous to human CEP44 (centrosomal protein 44). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 7.2), testis adult (RPKM 5.7) and 26 other tissues See more
Orthologs
human all
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Genomic context

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Location:
8 B2; 8 29.7 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (56983516..57010052, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (56531516..56550876, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930518J21 gene Neighboring gene STARR-seq mESC enhancer starr_21518 Neighboring gene predicted gene, 24375 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:59029623-59029732 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:59030027-59030210 Neighboring gene STARR-positive B cell enhancer mm9_chr8:59030212-59030513 Neighboring gene F-box protein 8 Neighboring gene ferritin light chain 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_21519 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Hein MY, et al. Cell, 2015 Oct 22. PMID 26496610
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  3. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851
  4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • KIAA1712, MGC113766

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in centriole replication ISO
Inferred from Sequence Orthology
more info
  
involved_in centriole-centriole cohesion ISO
Inferred from Sequence Orthology
more info
  
involved_in centrosome cycle ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in centriole ISO
Inferred from Sequence Orthology
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
is_active_in spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in spindle pole ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
centrosomal protein of 44 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009951.1 → NP_001009951.1  centrosomal protein of 44 kDa

    See identical proteins and their annotated locations for NP_001009951.1

    Status: PROVISIONAL

    Source sequence(s)
    BC088983
    Consensus CDS
    CCDS22313.1
    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Related
    ENSMUSP00000042586.9, ENSMUST00000040330.15
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    56983516..57010052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006509448.5 → XP_006509511.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_006509511.1

    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  2. XM_006509447.5 → XP_006509510.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_006509510.1

    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  3. XM_006509445.5 → XP_006509508.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_006509508.1

    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  4. XM_006509446.4 → XP_006509509.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_006509509.1

    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  5. XM_006509450.4 → XP_006509513.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_006509513.1

    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  6. XM_006509451.5 → XP_006509514.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_006509514.1

    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  7. XM_006509449.4 → XP_006509512.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_006509512.1

    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  8. XM_036154140.1 → XP_036010033.1  centrosomal protein of 44 kDa isoform X1

    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  9. XM_006509452.4 → XP_006509515.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_006509515.1

    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

  10. XM_017312870.2 → XP_017168359.1  centrosomal protein of 44 kDa isoform X1

    UniProtKB/Swiss-Prot
    Q5DTV5, Q5HZK1
    UniProtKB/TrEMBL
    F7BA57
    Conserved Domains (1) summary
    pfam15007
    Location:5 → 128
    CEP44; Centrosomal spindle body, CEP44

RNA

  1. XR_004934849.1 RNA Sequence

  2. XR_004934848.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5HZK1.1 GenPept UniProtKB/Swiss-Prot:Q5HZK1

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