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Ctxn2 cortexin 2 [ Mus musculus (house mouse) ]

Gene ID: 381418, updated on 5-Mar-2024

Summary

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Official Symbol
Ctxn2provided by MGI
Official Full Name
cortexin 2provided by MGI
Primary source
MGI:MGI:2139444
See related
Ensembl:ENSMUSG00000074872 AllianceGenome:MGI:2139444
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1638
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human CTXN2 (cortexin 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 5.3), cerebellum adult (RPKM 3.4) and 5 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 F1; 2 61.21 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (124978534..124989763)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (125136066..125147843)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene myelin basic protein expression factor 2, repressor Neighboring gene STARR-seq mESC enhancer starr_05583 Neighboring gene predicted gene, 22352 Neighboring gene predicted gene, 46759 Neighboring gene solute carrier family 12, member 1 Neighboring gene STARR-positive B cell enhancer mm9_chr2:125014961-125015261 Neighboring gene predicted gene, 46760 Neighboring gene predicted gene 14002

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cortexin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162934.2 → NP_001156406.3  cortexin-2

    Status: VALIDATED

    Source sequence(s)
    AL929451
    Consensus CDS
    CCDS50692.1
    UniProtKB/Swiss-Prot
    Q3URE8
    Related
    ENSMUSP00000158847.2, ENSMUST00000238377.2
    Conserved Domains (1) summary
    pfam11057
    Location:9 → 81
    Cortexin; Cortexin of kidney

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    124978534..124989763
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006499833.4 → XP_006499896.1  cortexin-2 isoform X1

    See identical proteins and their annotated locations for XP_006499896.1

    UniProtKB/TrEMBL
    A0A0R4J179
    Related
    ENSMUSP00000158834.2, ENSMUST00000238754.2
    Conserved Domains (1) summary
    pfam11057
    Location:10 → 82
    Cortexin; Cortexin of kidney

  2. XM_006499835.3 → XP_006499898.1  cortexin-2 isoform X1

    See identical proteins and their annotated locations for XP_006499898.1

    UniProtKB/TrEMBL
    A0A0R4J179
    Conserved Domains (1) summary
    pfam11057
    Location:10 → 82
    Cortexin; Cortexin of kidney

  3. XM_006499834.5 → XP_006499897.1  cortexin-2 isoform X1

    See identical proteins and their annotated locations for XP_006499897.1

    UniProtKB/TrEMBL
    A0A0R4J179
    Conserved Domains (1) summary
    pfam11057
    Location:10 → 82
    Cortexin; Cortexin of kidney
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3URE8.2 GenPept UniProtKB/Swiss-Prot:Q3URE8

Gene LinkOut

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