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Crocc2 ciliary rootlet coiled-coil, rootletin family member 2 [ Mus musculus (house mouse) ]

Gene ID: 381284, updated on 5-Mar-2024

Summary

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Official Symbol
Crocc2provided by MGI
Official Full Name
ciliary rootlet coiled-coil, rootletin family member 2provided by MGI
Primary source
MGI:MGI:3045962
See related
Ensembl:ENSMUSG00000084989 AllianceGenome:MGI:3045962
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm976; E030010N08Rik
Summary
Is expressed in central nervous system; dorsal root ganglion; embryo mesenchyme; and lung. Orthologous to human CROCC2 (ciliary rootlet coiled-coil, rootletin family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in ovary adult (RPKM 2.5), lung adult (RPKM 1.1) and 6 other tissues See more
Orthologs
human all
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Genomic context

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Location:
1 D; 1 47.17 cM
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (93096145..93158789)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (93168423..93231067)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene alanine-glyoxylate aminotransferase Neighboring gene mab-21-like 4 Neighboring gene STARR-seq mESC enhancer starr_01724 Neighboring gene STARR-seq mESC enhancer starr_01726 Neighboring gene sushi, nidogen and EGF-like domains 1 Neighboring gene microRNA 6901 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:95202393-95202604 Neighboring gene mitochondrial transcription termination factor 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Stauber M, et al. Dev Biol, 2017 Mar 15. PMID 27914912
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ciliary rootlet coiled-coil protein 2
Names
putative ciliary rootlet coiled-coil protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310428.1 → NP_001297357.1  ciliary rootlet coiled-coil protein 2

    Status: PROVISIONAL

    Source sequence(s)
    AC103673, AC124669
    Consensus CDS
    CCDS78654.1
    UniProtKB/Swiss-Prot
    F6XLV1
    Related
    ENSMUSP00000120588.3, ENSMUST00000138595.3
    Conserved Domains (2) summary
    TIGR02168
    Location:431 → 1248
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15035
    Location:128 → 259
    Rootletin; Ciliary rootlet component, centrosome cohesion

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    93096145..93158789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529983.2 → XP_006530046.1  ciliary rootlet coiled-coil protein 2 isoform X1

    Conserved Domains (2) summary
    TIGR02168
    Location:435 → 1248
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15035
    Location:119 → 259
    Rootletin; Ciliary rootlet component, centrosome cohesion

  2. XM_006529986.2 → XP_006530049.1  ciliary rootlet coiled-coil protein 2 isoform X4

    Conserved Domains (2) summary
    TIGR02168
    Location:435 → 1248
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15035
    Location:119 → 259
    Rootletin; Ciliary rootlet component, centrosome cohesion

  3. XM_036166086.1 → XP_036021979.1  ciliary rootlet coiled-coil protein 2 isoform X5

    Conserved Domains (2) summary
    TIGR02168
    Location:435 → 1241
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15035
    Location:128 → 259
    Rootletin; Ciliary rootlet component, centrosome cohesion

  4. XM_006529984.2 → XP_006530047.1  ciliary rootlet coiled-coil protein 2 isoform X2

    Conserved Domains (2) summary
    TIGR02168
    Location:433 → 1246
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15035
    Location:119 → 257
    Rootletin; Ciliary rootlet component, centrosome cohesion

  5. XM_030255127.1 → XP_030110987.1  ciliary rootlet coiled-coil protein 2 isoform X6

    Conserved Domains (2) summary
    TIGR02168
    Location:290 → 1103
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15035
    Location:18 → 114
    Rootletin; Ciliary rootlet component, centrosome cohesion

  6. XM_006529994.2 → XP_006530057.1  ciliary rootlet coiled-coil protein 2 isoform X9

    See identical proteins and their annotated locations for XP_006530057.1

    Conserved Domains (2) summary
    TIGR02168
    Location:435 → 1248
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15035
    Location:119 → 259
    Rootletin; Ciliary rootlet component, centrosome cohesion

  7. XM_006529985.2 → XP_006530048.1  ciliary rootlet coiled-coil protein 2 isoform X3

    Conserved Domains (2) summary
    TIGR02168
    Location:432 → 1245
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15035
    Location:116 → 256
    Rootletin; Ciliary rootlet component, centrosome cohesion

  8. XM_006529991.3 → XP_006530054.1  ciliary rootlet coiled-coil protein 2 isoform X7

    Conserved Domains (2) summary
    TIGR02168
    Location:272 → 1085
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15035
    Location:2 → 96
    Rootletin; Ciliary rootlet component, centrosome cohesion

  9. XM_006529992.2 → XP_006530055.1  ciliary rootlet coiled-coil protein 2 isoform X8

    Conserved Domains (1) summary
    TIGR02168
    Location:264 → 1077
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RNA

  1. XR_004942947.1 RNA Sequence

  2. XR_003956157.1 RNA Sequence

  3. XR_003956159.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F6XLV1.2 GenPept UniProtKB/Swiss-Prot:F6XLV1

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