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Tmem151a transmembrane protein 151A [ Mus musculus (house mouse) ]

Gene ID: 381199, updated on 5-Mar-2024

Summary

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Official Symbol
Tmem151aprovided by MGI
Official Full Name
transmembrane protein 151Aprovided by MGI
Primary source
MGI:MGI:2147713
See related
Ensembl:ENSMUSG00000061451 AllianceGenome:MGI:2147713
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm961; Gm30627; Tmem151
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in diencephalon mantle layer; hypothalamus mantle layer; and thalamus mantle layer. Orthologous to human TMEM151A (transmembrane protein 151A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in stomach adult (RPKM 43.1), cortex adult (RPKM 36.1) and 8 other tissues See more
Orthologs
human all
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Genomic context

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Location:
19; 19 A
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5120859..5135519, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5079333..5085491, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene Ras and Rab interactor 1 Neighboring gene STARR-positive B cell enhancer ABC_E1968 Neighboring gene uncharacterized LOC132660285 Neighboring gene STARR-positive B cell enhancer ABC_E7627 Neighboring gene CD248 antigen, endosialin Neighboring gene Yip1 interacting factor homolog A (S. cerevisiae) Neighboring gene cornichon family AMPA receptor auxiliary protein 2 Neighboring gene RAB1B, member RAS oncogene family Neighboring gene STARR-positive B cell enhancer ABC_E1969

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. TMEM151A variants cause paroxysmal kinesigenic dyskinesia. Li HF, et al. Cell Discov, 2021 Sep 13. PMID 34518509, Free PMC Article
  2. A genomic atlas of mouse hypothalamic development. Shimogori T, et al. Nat Neurosci, 2010 Jun. PMID 20436479, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
transmembrane protein 151A
Names
transmembrane protein 151

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001885.2 → NP_001001885.1  transmembrane protein 151A

    See identical proteins and their annotated locations for NP_001001885.1

    Status: VALIDATED

    Source sequence(s)
    AC124502, BC072634
    Consensus CDS
    CCDS29449.1
    UniProtKB/Swiss-Prot
    Q6GQT5
    Related
    ENSMUSP00000076321.8, ENSMUST00000077066.8
    Conserved Domains (1) summary
    pfam14857
    Location:26 → 423
    TMEM151; TMEM151 family

RNA

  1. NR_166780.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124502

  2. NR_166781.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124502

  3. NR_166782.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124502

  4. NR_166783.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124502

  5. NR_166784.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124502
    Related
    ENSMUST00000143677.2

  6. NR_166785.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124502

  7. NR_166786.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124502

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    5120859..5135519 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6GQT5.1 GenPept UniProtKB/Swiss-Prot:Q6GQT5

Gene LinkOut

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