U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ccdc68 coiled-coil domain containing 68 [ Mus musculus (house mouse) ]

Gene ID: 381175, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Ccdc68provided by MGI
Official Full Name
coiled-coil domain containing 68provided by MGI
Primary source
MGI:MGI:3612676
See related
Ensembl:ENSMUSG00000038903 AllianceGenome:MGI:3612676
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in intracellular signal transduction; microtubule anchoring at centrosome; and protein localization. Predicted to be located in centriole. Predicted to be part of centriolar subdistal appendage. Orthologous to human CCDC68 (coiled-coil domain containing 68). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in placenta adult (RPKM 9.7), bladder adult (RPKM 2.2) and 8 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
18 E2; 18 43.78 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (70057929..70102559)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (69924858..69969488)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31564 Neighboring gene STARR-seq mESC enhancer starr_44954 Neighboring gene predicted gene, 36175 Neighboring gene STARR-seq mESC enhancer starr_44955 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene RAB27B, member RAS oncogene family Neighboring gene STARR-seq mESC enhancer starr_44957 Neighboring gene predicted gene, 41770 Neighboring gene STARR-seq mESC enhancer starr_44958 Neighboring gene dynactin associated protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC54896

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule anchoring at centrosome ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of centriolar subdistal appendage ISO
Inferred from Sequence Orthology
more info
  
located_in centriole ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
is_active_in intracellular anatomical structure IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
coiled-coil domain-containing protein 68

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201362.2 → NP_958750.1  coiled-coil domain-containing protein 68

    See identical proteins and their annotated locations for NP_958750.1

    Status: PROVISIONAL

    Source sequence(s)
    AK078964
    Consensus CDS
    CCDS29330.1
    UniProtKB/Swiss-Prot
    Q80VD6, Q8BVC4
    Related
    ENSMUSP00000046197.5, ENSMUST00000043929.11
    Conserved Domains (1) summary
    COG1196
    Location:68 → 294
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    70057929..70102559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006526070.3 → XP_006526133.1  coiled-coil domain-containing protein 68 isoform X1

    Conserved Domains (1) summary
    COG1196
    Location:144 → 396
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_006526071.3 → XP_006526134.1  coiled-coil domain-containing protein 68 isoform X2

    Conserved Domains (1) summary
    COG1196
    Location:144 → 370
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. XM_006526076.3 → XP_006526139.1  coiled-coil domain-containing protein 68 isoform X4

    See identical proteins and their annotated locations for XP_006526139.1

    Conserved Domains (1) summary
    COG1196
    Location:68 → 320
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  4. XM_017317935.1 → XP_017173424.1  coiled-coil domain-containing protein 68 isoform X3

    Conserved Domains (1) summary
    COG1196
    Location:73 → 325
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  5. XM_006526075.3 → XP_006526138.1  coiled-coil domain-containing protein 68 isoform X4

    See identical proteins and their annotated locations for XP_006526138.1

    Conserved Domains (1) summary
    COG1196
    Location:68 → 320
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  6. XM_006526074.3 → XP_006526137.1  coiled-coil domain-containing protein 68 isoform X4

    See identical proteins and their annotated locations for XP_006526137.1

    Conserved Domains (1) summary
    COG1196
    Location:68 → 320
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  7. XM_011246971.3 → XP_011245273.1  coiled-coil domain-containing protein 68 isoform X4

    See identical proteins and their annotated locations for XP_011245273.1

    Conserved Domains (1) summary
    COG1196
    Location:68 → 320
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BVC4.1 GenPept UniProtKB/Swiss-Prot:Q8BVC4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous