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Zfp948 zinc finger protein 948 [ Mus musculus (house mouse) ]

Gene ID: 381066, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp948provided by MGI
Official Full Name
zinc finger protein 948provided by MGI
Primary source
MGI:MGI:3040683
See related
Ensembl:ENSMUSG00000067931 AllianceGenome:MGI:3040683
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in placenta adult (RPKM 6.3), CNS E18 (RPKM 3.0) and 16 other tissues See more
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Genomic context

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Location:
17 A3.2; 17 11.4 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (21786082..21809586)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (21565816..21589324)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3186 Neighboring gene zinc finger protein 53 Neighboring gene RIKEN cDNA 9330136K24 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:21669090-21669243 Neighboring gene zinc finger protein 52 Neighboring gene STARR-positive B cell enhancer ABC_E9942 Neighboring gene predicted gene, 30531 Neighboring gene predicted gene, 41541 Neighboring gene zinc finger protein 983 Neighboring gene predicted gene, 53991

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
  2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 948

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002008.2 → NP_001002008.1  zinc finger protein 948

    See identical proteins and their annotated locations for NP_001002008.1

    Status: VALIDATED

    Source sequence(s)
    BC076634, CN723670, CT010433
    Consensus CDS
    CCDS28441.1
    UniProtKB/TrEMBL
    Q6DFU8
    Related
    ENSMUSP00000086166.6, ENSMUST00000088787.7
    Conserved Domains (4) summary
    COG5048
    Location:195 → 595
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:216 → 236
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
    pfam13465
    Location:591 → 615
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001357347.1 → NP_001344276.1  zinc finger protein 948

    Status: VALIDATED

    Source sequence(s)
    BC076634, CAAA01190167, CT010433
    Consensus CDS
    CCDS28441.1
    UniProtKB/TrEMBL
    Q6DFU8
    Conserved Domains (4) summary
    COG5048
    Location:195 → 595
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:216 → 236
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
    pfam13465
    Location:591 → 615
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    21786082..21809586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036160668.1 → XP_036016561.1  zinc finger protein 948 isoform X1

    UniProtKB/TrEMBL
    Q6DFU8
    Conserved Domains (4) summary
    COG5048
    Location:195 → 595
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:216 → 236
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
    pfam13465
    Location:591 → 615
    zf-H2C2_2; Zinc-finger double domain

  2. XM_036160669.1 → XP_036016562.1  zinc finger protein 948 isoform X1

    UniProtKB/TrEMBL
    Q6DFU8
    Conserved Domains (4) summary
    COG5048
    Location:195 → 595
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:216 → 236
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
    pfam13465
    Location:591 → 615
    zf-H2C2_2; Zinc-finger double domain

  3. XM_030249859.2 → XP_030105719.1  zinc finger protein 948 isoform X1

    UniProtKB/TrEMBL
    Q6DFU8
    Conserved Domains (4) summary
    COG5048
    Location:195 → 595
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:216 → 236
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
    pfam13465
    Location:591 → 615
    zf-H2C2_2; Zinc-finger double domain

  4. XM_036160667.1 → XP_036016560.1  zinc finger protein 948 isoform X1

    UniProtKB/TrEMBL
    Q6DFU8
    Conserved Domains (4) summary
    COG5048
    Location:195 → 595
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:216 → 236
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
    pfam13465
    Location:591 → 615
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

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