mthl8 methuselah-like 8 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mthl8provided by FlyBase
Official Full Name: methuselah-like 8provided by FlyBase
Primary source: FLYBASE:FBgn0052475
Locus tag: Dmel_CG32475
See related: AllianceGenome:FB:FBgn0052475
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0170980.145; anon-WO0170980.146; CG11869; CG13406; CG32475; Dmel\CG32475; Mth-8; mthl-8; Mthl8
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; determination of adult lifespan; and response to starvation. Predicted to be integral component of membrane. Is expressed in embryonic/larval optic lobe; eye disc posterior to the morphogenetic furrow; morphogenetic furrow; and ocellar triangle. Orthologous to human ADGRF3 (adhesion G protein-coupled receptor F3). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (22428..26308)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (22428..26308)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables G protein-coupled peptide receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables G protein-coupled receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in G protein-coupled receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in determination of adult lifespan	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to starvation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

Names: CG32475-PA; CG32475-PB; Methuselah-like 8; mth-like 8; mthl8-PA; mthl8-PB

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