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Ltv1 LTV1 ribosome biogenesis factor [ Mus musculus (house mouse) ]

Gene ID: 353258, updated on 11-Apr-2024

Summary

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Official Symbol
Ltv1provided by MGI
Official Full Name
LTV1 ribosome biogenesis factorprovided by MGI
Primary source
MGI:MGI:2447810
See related
Ensembl:ENSMUSG00000019814 AllianceGenome:MGI:2447810
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610020N02Rik
Summary
Predicted to be involved in ribosomal small subunit biogenesis and ribosomal small subunit export from nucleus. Predicted to be located in nucleoplasm. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Is expressed in early conceptus; limb digit; nose; oocyte; and skeleton. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 14.6), placenta adult (RPKM 12.9) and 25 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10 A2; 10 4.72 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (13054341..13068881, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (13178597..13193137, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_25810 Neighboring gene pleiomorphic adenoma gene-like 1 Neighboring gene hydatidiform mole associated and imprinted transcript Neighboring gene zinc finger, C2HC-type containing 1B Neighboring gene STARR-seq mESC enhancer starr_25812 Neighboring gene phosphatase and actin regulator 2 Neighboring gene predicted gene, 46211 Neighboring gene STARR-seq mESC enhancer starr_25813 Neighboring gene STARR-seq mESC enhancer starr_25814 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:13220839-13220948 Neighboring gene fucosidase, alpha-L- 2, plasma

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Expression patterns of novel genes during mouse preimplantation embryogenesis. Temeles GL, et al. Mol Reprod Dev, 1994 Feb. PMID 7545925
  2. ATG5 is required for B cell polarization and presentation of particulate antigens. Arbogast F, et al. Autophagy, 2019 Feb. PMID 30196744, Free PMC Article
  3. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in ribosomal small subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of preribosome, small subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein LTV1 homolog
Names
LTV1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181470.4 → NP_852135.1  protein LTV1 homolog

    See identical proteins and their annotated locations for NP_852135.1

    Status: PROVISIONAL

    Source sequence(s)
    BC067062
    Consensus CDS
    CCDS35845.1
    UniProtKB/Swiss-Prot
    Q6NSQ7, Q9D0F5
    Related
    ENSMUSP00000019950.5, ENSMUST00000019950.6
    Conserved Domains (2) summary
    pfam04180
    Location:15 → 440
    LTV; Low temperature viability protein
    pfam08079
    Location:422 → 462
    Ribosomal_L30_N; Ribosomal L30 N-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    13054341..13068881 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512776.4 → XP_006512839.1  protein LTV1 homolog isoform X1

    Conserved Domains (1) summary
    pfam04180
    Location:1 → 266
    LTV; Low temperature viability protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6NSQ7.2 GenPept UniProtKB/Swiss-Prot:Q6NSQ7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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