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CG6583 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34645, updated on 4-Apr-2024

Summary

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Official Symbol
CG6583provided by FlyBase
Primary source
FLYBASE:FBgn0032420
Locus tag
Dmel_CG6583
See related
AllianceGenome:FB:FBgn0032420
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6583; EN2-9
Summary
Predicted to be involved in positive regulation of voltage-gated potassium channel activity; regulation of cholinergic synaptic transmission; and sleep. Located in cytosol. Is expressed in adult brain cell body rind and adult head. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
33D2-33D2; 2-46 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12171204..12172586, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12171204..12172586, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43356 Neighboring gene uncharacterized protein Neighboring gene Zinc transporter 33D Neighboring gene uncharacterized protein Neighboring gene atilla Neighboring gene crooked Neighboring gene bruno 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family. Tanaka K, et al. Mol Biol Evol, 2015 Jul. PMID 25743545, Free PMC Article
  2. The nucleolar protein Viriato/Nol12 is required for the growth and differentiation progression activities of the Dpp pathway during Drosophila eye development. Marinho J, et al. Dev Biol, 2013 May 1. PMID 23416177
  3. A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene. Gavory G, et al. PLoS Genet, 2021 Aug. PMID 34383740, Free PMC Article
  4. Crooked, coiled and crimpled are three Ly6-like proteins required for proper localization of septate junction components. Nilton A, et al. Development, 2010 Jul. PMID 20570942, Free PMC Article
  5. Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets. Hong X, et al. Proc Natl Acad Sci U S A, 2009 Sep 1. PMID 19706460, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in regulation of synaptic transmission, cholinergic IEA
Inferred from Electronic Annotation
more info
  
involved_in sleep IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol HDA PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG6583-PA
enhancer of NA9 2-9

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    12171204..12172586 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135712.4 → NP_609556.2  uncharacterized protein Dmel_CG6583 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609556.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZ82, Q9VKA1
    Related
    FBpp0079940
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SZ82 Q8SZ82
Q9VKA1 Q9VKA1

Gene LinkOut

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