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CG13784 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34003, updated on 4-Apr-2024

Summary

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Official Symbol
CG13784provided by FlyBase
Primary source
FLYBASE:FBgn0031897
Locus tag
Dmel_CG13784
See related
AllianceGenome:FB:FBgn0031897
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:SD10385; Dmel\CG13784
Summary
Predicted to be involved in phospholipid translocation and retrograde transport, endosome to Golgi. Predicted to be active in endosome and trans-Golgi network. Is expressed in several structures, including adult head; anterior endoderm anlage; ectoderm anlage; germ layer; and ventral nerve cord primordium. Orthologous to human SLC66A2 (solute carrier family 66 member 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
27E4-27E5; 2-25 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7204538..7220033, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7204538..7220033, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44989 Neighboring gene mitochondrial translation elongation factor G 1 Neighboring gene Na[+]-driven anion exchanger 1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Drosophila mitochondrial translation elongation factor G1 contains a nuclear localization signal and inhibits growth and DPP signaling. Trivigno C, et al. PLoS One, 2011 Feb 25. PMID 21364917, Free PMC Article
  2. Steroid hormone control of cell death and cell survival: molecular insights using RNAi. Chittaranjan S, et al. PLoS Genet, 2009 Feb. PMID 19214204, Free PMC Article
  3. The Identification and Evolutionary Trends of the Solute Carrier Superfamily in Arthropods. Denecke SM, et al. Genome Biol Evol, 2020 Aug 1. PMID 32681801, Free PMC Article
  4. Identification of conserved transcriptome features between humans and Drosophila in the aging brain utilizing machine learning on combined data from the NIH Sequence Read Archive. Webb JL, et al. PLoS One, 2021. PMID 34379632, Free PMC Article
  5. Isolation of gene sets affected specifically by polyglutamine expression: implication of the TOR signaling pathway in neurodegeneration. Nelson B, et al. Cell Death Differ, 2005 Aug. PMID 15861189

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in phospholipid translocation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG13784-PB
CG13784-PC
CG13784-PD
CG13784-PE
CG13784-PF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7204538..7220033 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273245.2 → NP_001260174.1  uncharacterized protein Dmel_CG13784, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260174.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PCT0
    Conserved Domains (1) summary
    pfam04193
    Location:185 → 240
    PQ-loop; PQ loop repeat

  2. NM_001273246.2 → NP_001260175.1  uncharacterized protein Dmel_CG13784, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260175.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PCE7
    Conserved Domains (1) summary
    pfam04193
    Location:193 → 248
    PQ-loop; PQ loop repeat

  3. NM_001273247.2 → NP_001260176.1  uncharacterized protein Dmel_CG13784, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260176.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PEZ6
    Conserved Domains (1) summary
    pfam04193
    Location:193 → 248
    PQ-loop; PQ loop repeat

  4. NM_001042878.4 → NP_001036343.2  uncharacterized protein Dmel_CG13784, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036343.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E8S5
    Conserved Domains (1) summary
    pfam04193
    Location:193 → 248
    PQ-loop; PQ loop repeat

  5. NM_164742.3 → NP_723261.1  uncharacterized protein Dmel_CG13784, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723261.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9A4
    Related
    FBpp0079042
    Conserved Domains (1) summary
    pfam04193
    Location:18 → 67
    PQ-loop; PQ loop repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PCE7 M9PCE7
M9PCT0 M9PCT0
M9PEZ6 M9PEZ6
Q0E8S5 Q0E8S5
Q8T9A4 Q8T9A4
Q95SN2 Q95SN2

Gene LinkOut

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