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ARMH1 armadillo like helical domain containing 1 [ Homo sapiens (human) ]

Gene ID: 339541, updated on 3-Apr-2024

Summary

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Official Symbol
ARMH1provided by HGNC
Official Full Name
armadillo like helical domain containing 1provided by HGNC
Primary source
HGNC:HGNC:34345
See related
Ensembl:ENSG00000198520 AllianceGenome:HGNC:34345
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
p40; C1orf228; NCRNA00082
Expression
Biased expression in bone marrow (RPKM 8.3), testis (RPKM 3.2) and 6 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
1p34.1
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (44674714..44725591)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (44545660..44596534)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (45140386..45191263)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ring finger protein 220 Neighboring gene uncharacterized LOC107984950 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:45115956-45116537 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 942 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:45139597-45140098 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 813 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 814 Neighboring gene transmembrane protein 53 Neighboring gene uncharacterized LOC105378690 Neighboring gene small nucleolar RNA, C/D box 145 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 815 Neighboring gene Sharpr-MPRA regulatory region 12667 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 816 Neighboring gene Sharpr-MPRA regulatory region 12642 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:45200330-45200889 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 943 Neighboring gene RNA, U5F small nuclear 1 Neighboring gene RNA, U5D small nuclear 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 944 Neighboring gene kinesin family member 2C Neighboring gene small nucleolar RNA, C/D box 160

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors. Feng X, et al. Sci Adv, 2022 May 13. PMID 35559673, Free PMC Article
  2. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. Choudhury NR, et al. BMC Biol, 2017 Nov 8. PMID 29117863, Free PMC Article
  3. Architecture of the human interactome defines protein communities and disease networks. Huttlin EL, et al. Nature, 2017 May 25. PMID 28514442, Free PMC Article
  4. Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Huttlin EL, et al. Cell, 2021 May 27. PMID 33961781, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC33556

General protein information

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Preferred Names
armadillo-like helical domain containing protein 1
Names
uncharacterized protein C1orf228

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145636.2 → NP_001139108.1  armadillo-like helical domain containing protein 1

    See identical proteins and their annotated locations for NP_001139108.1

    Status: VALIDATED

    Source sequence(s)
    AL122004, AY254217, BC026115, BX112141
    Consensus CDS
    CCDS53311.1
    UniProtKB/Swiss-Prot
    A1KXE5, Q6PIY5
    Related
    ENSP00000440524.1, ENST00000535358.6

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    44674714..44725591
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541340.2 → XP_011539642.1  armadillo-like helical domain containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011539642.1

    Conserved Domains (1) summary
    pfam17741
    Location:1 → 268
    DUF5578; Family of unknown function (DUF5578)

  2. XM_006710603.3 → XP_006710666.1  armadillo-like helical domain containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006710666.1

    Conserved Domains (1) summary
    pfam17741
    Location:1 → 268
    DUF5578; Family of unknown function (DUF5578)

  3. XM_011541345.2 → XP_011539647.1  armadillo-like helical domain containing protein 1 isoform X2

    Conserved Domains (1) summary
    pfam17741
    Location:1 → 255
    DUF5578; Family of unknown function (DUF5578)

  4. XM_006710604.3 → XP_006710667.1  armadillo-like helical domain containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006710667.1

    Conserved Domains (1) summary
    pfam17741
    Location:1 → 268
    DUF5578; Family of unknown function (DUF5578)

  5. XM_011541343.2 → XP_011539645.1  armadillo-like helical domain containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011539645.1

    Conserved Domains (1) summary
    pfam17741
    Location:1 → 268
    DUF5578; Family of unknown function (DUF5578)

  6. XM_047419337.1 → XP_047275293.1  armadillo-like helical domain containing protein 1 isoform X1

  7. XM_047419352.1 → XP_047275308.1  armadillo-like helical domain containing protein 1 isoform X3

  8. XM_011541341.2 → XP_011539643.1  armadillo-like helical domain containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011539643.1

    Conserved Domains (1) summary
    pfam17741
    Location:1 → 268
    DUF5578; Family of unknown function (DUF5578)

  9. XM_047419358.1 → XP_047275314.1  armadillo-like helical domain containing protein 1 isoform X5

  10. XM_017001142.2 → XP_016856631.1  armadillo-like helical domain containing protein 1 isoform X6

    Conserved Domains (1) summary
    pfam17741
    Location:1 → 268
    DUF5578; Family of unknown function (DUF5578)

  11. XM_017001143.2 → XP_016856632.1  armadillo-like helical domain containing protein 1 isoform X9

    Conserved Domains (1) summary
    pfam17741
    Location:1 → 268
    DUF5578; Family of unknown function (DUF5578)

  12. XM_011541349.3 → XP_011539651.1  armadillo-like helical domain containing protein 1 isoform X8

    Conserved Domains (1) summary
    pfam17741
    Location:1 → 198
    DUF5578; Family of unknown function (DUF5578)

  13. XM_047419380.1 → XP_047275336.1  armadillo-like helical domain containing protein 1 isoform X18

  14. XM_047419371.1 → XP_047275327.1  armadillo-like helical domain containing protein 1 isoform X14

  15. XM_047419362.1 → XP_047275318.1  armadillo-like helical domain containing protein 1 isoform X7

  16. XM_047419353.1 → XP_047275309.1  armadillo-like helical domain containing protein 1 isoform X4

  17. XM_047419367.1 → XP_047275323.1  armadillo-like helical domain containing protein 1 isoform X10

  18. XM_047419369.1 → XP_047275325.1  armadillo-like helical domain containing protein 1 isoform X11

  19. XM_047419370.1 → XP_047275326.1  armadillo-like helical domain containing protein 1 isoform X13

  20. XM_017001144.2 → XP_016856633.1  armadillo-like helical domain containing protein 1 isoform X12

    Conserved Domains (1) summary
    pfam17741
    Location:1 → 268
    DUF5578; Family of unknown function (DUF5578)

  21. XM_017001146.3 → XP_016856635.1  armadillo-like helical domain containing protein 1 isoform X16

    UniProtKB/TrEMBL
    C9JCY2
    Related
    ENSP00000420664.1, ENST00000441519.5
    Conserved Domains (1) summary
    pfam17741
    Location:1 → 242
    DUF5578; Family of unknown function (DUF5578)

  22. XM_017001147.2 → XP_016856636.1  armadillo-like helical domain containing protein 1 isoform X17

    UniProtKB/TrEMBL
    C9JCY2
    Related
    ENSP00000417998.1, ENST00000445071.5
    Conserved Domains (1) summary
    pfam17741
    Location:1 → 241
    DUF5578; Family of unknown function (DUF5578)

  23. XM_017001145.2 → XP_016856634.1  armadillo-like helical domain containing protein 1 isoform X15

    UniProtKB/TrEMBL
    C9JCY2
    Conserved Domains (1) summary
    pfam17741
    Location:1 → 242
    DUF5578; Family of unknown function (DUF5578)

RNA

  1. XR_007059336.1 RNA Sequence

  2. XR_001737140.2 RNA Sequence

    Related
    ENST00000357508.5

  3. XR_001737141.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    44545660..44596534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054336284.1 → XP_054192259.1  armadillo-like helical domain containing protein 1 isoform X1

  2. XM_054336283.1 → XP_054192258.1  armadillo-like helical domain containing protein 1 isoform X1

  3. XM_054336286.1 → XP_054192261.1  armadillo-like helical domain containing protein 1 isoform X2

  4. XM_054336285.1 → XP_054192260.1  armadillo-like helical domain containing protein 1 isoform X1

  5. XM_054336281.1 → XP_054192256.1  armadillo-like helical domain containing protein 1 isoform X1

  6. XM_054336282.1 → XP_054192257.1  armadillo-like helical domain containing protein 1 isoform X1

  7. XM_054336287.1 → XP_054192262.1  armadillo-like helical domain containing protein 1 isoform X3

  8. XM_054336280.1 → XP_054192255.1  armadillo-like helical domain containing protein 1 isoform X1

  9. XM_054336289.1 → XP_054192264.1  armadillo-like helical domain containing protein 1 isoform X5

  10. XM_054336290.1 → XP_054192265.1  armadillo-like helical domain containing protein 1 isoform X6

  11. XM_054336293.1 → XP_054192268.1  armadillo-like helical domain containing protein 1 isoform X9

  12. XM_054336292.1 → XP_054192267.1  armadillo-like helical domain containing protein 1 isoform X8

  13. XM_054336302.1 → XP_054192277.1  armadillo-like helical domain containing protein 1 isoform X18

  14. XM_054336298.1 → XP_054192273.1  armadillo-like helical domain containing protein 1 isoform X14

  15. XM_054336291.1 → XP_054192266.1  armadillo-like helical domain containing protein 1 isoform X7

  16. XM_054336288.1 → XP_054192263.1  armadillo-like helical domain containing protein 1 isoform X4

  17. XM_054336294.1 → XP_054192269.1  armadillo-like helical domain containing protein 1 isoform X10

  18. XM_054336295.1 → XP_054192270.1  armadillo-like helical domain containing protein 1 isoform X11

  19. XM_054336297.1 → XP_054192272.1  armadillo-like helical domain containing protein 1 isoform X13

  20. XM_054336296.1 → XP_054192271.1  armadillo-like helical domain containing protein 1 isoform X12

  21. XM_054336300.1 → XP_054192275.1  armadillo-like helical domain containing protein 1 isoform X16

  22. XM_054336301.1 → XP_054192276.1  armadillo-like helical domain containing protein 1 isoform X17

  23. XM_054336299.1 → XP_054192274.1  armadillo-like helical domain containing protein 1 isoform X15

RNA

  1. XR_008486019.1 RNA Sequence

  2. XR_008486017.1 RNA Sequence

  3. XR_008486018.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001004307.2: Suppressed sequence

    Description
    NM_001004307.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PIY5.2 GenPept UniProtKB/Swiss-Prot:Q6PIY5

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