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Cyp28d1 Cytochrome P450 28d1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33749, updated on 4-Apr-2024

Summary

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Official Symbol
Cyp28d1provided by FlyBase
Official Full Name
Cytochrome P450 28d1provided by FlyBase
Primary source
FLYBASE:FBgn0031689
Locus tag
Dmel_CG10833
See related
AllianceGenome:FB:FBgn0031689
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
28d1; CG10833; CYP28d1; Dmel\CG10833
Summary
Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. Is expressed in several structures, including adult head; embryonic/larval Malpighian tubule; embryonic/larval midgut; and embryonic/larval trachea. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
25C10-25C10; 2-15 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5210460..5212445)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5210460..5212445)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Muscle-specific protein 300 kDa Neighboring gene small non-coding RNA 158 Neighboring gene Cytochrome P450 28d2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Troponin C at 25D Neighboring gene thickveins

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dynamics and stage-specificity of between-population gene expression divergence in the Drosophila melanogaster larval fat body. Glaser-Schmitt A, et al. PLoS Genet, 2023 Apr. PMID 37099612, Free PMC Article
  2. Naturally Segregating Variation at Ugt86Dd Contributes to Nicotine Resistance in Drosophila melanogaster. Highfill CA, et al. Genetics, 2017 Sep. PMID 28743761, Free PMC Article
  3. Selenoprotein dSelK in Drosophila elevates release of Ca2+ from endoplasmic reticulum by upregulating expression of inositol 1,4,5-tris-phosphate receptor. Ben SB, et al. Biochemistry (Mosc), 2011 Sep. PMID 22082272
  4. Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits. Chakraborty M, et al. Nat Commun, 2019 Oct 25. PMID 31653862, Free PMC Article
  5. Metabolic activation and toxicological evaluation of polychlorinated biphenyls in Drosophila melanogaster. Idda T, et al. Sci Rep, 2020 Dec 9. PMID 33299007, Free PMC Article

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytochrome P450 28d1
Names
CG10833-PA
Cyp28d1-PA
cytochrome P450
NP_608912.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    5210460..5212445
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135068.4 → NP_608912.1  cytochrome P450 28d1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608912.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VMT5
    Related
    FBpp0078698
    Conserved Domains (1) summary
    pfam00067
    Location:35 → 477
    p450; Cytochrome P450
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VMT5.1 Q9VMT5

Gene LinkOut

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