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CG16704 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33589, updated on 4-Apr-2024

Summary

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Official Symbol
CG16704provided by FlyBase
Primary source
FLYBASE:FBgn0031558
Locus tag
Dmel_CG16704
See related
AllianceGenome:FB:FBgn0031558
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH31195; CT37177; Dmel\CG16704
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Orthologous to human WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
24B1-24B1; 2-10 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3692123..3692587, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3692123..3692587, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Dorsal root ganglia homeobox Neighboring gene Seminal fluid protein 24Bb Neighboring gene Seminal fluid protein 24Bc Neighboring gene uncharacterized protein Neighboring gene Accessory gland protein 24A4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation. Garelli A, et al. Science, 2012 May 4. PMID 22556250
  2. Genome-wide phenotypic RNAi screen in the Drosophila wing: global parameters. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599819, Free PMC Article
  3. Genome-wide gene expression in response to parasitoid attack in Drosophila. Wertheim B, et al. Genome Biol, 2005. PMID 16277749, Free PMC Article
  4. Evolution of a cellular immune response in Drosophila: a phenotypic and genomic comparative analysis. Salazar-Jaramillo L, et al. Genome Biol Evol, 2014 Feb. PMID 24443439, Free PMC Article
  5. Drosophila anti-nematode and antibacterial immune regulators revealed by RNA-Seq. Castillo JC, et al. BMC Genomics, 2015 Jul 11. PMID 26162375, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG16704-PA
CG16704-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    3692123..3692587 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298664.1 → NP_001285593.1  uncharacterized protein Dmel_CG16704, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285593.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SY86, Q9VQT5
    Conserved Domains (1) summary
    cl00101
    Location:34 → 78
    KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.

  2. NM_134953.4 → NP_608797.1  uncharacterized protein Dmel_CG16704, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608797.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SY86, Q9VQT5
    Related
    FBpp0077239
    Conserved Domains (1) summary
    cl00101
    Location:34 → 78
    KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SY86 Q8SY86
Q9VQT5 Q9VQT5

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