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Tigd3 tigger transposable element derived 3 [ Mus musculus (house mouse) ]

Gene ID: 332359, updated on 11-Apr-2024

Summary

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Official Symbol
Tigd3provided by MGI
Official Full Name
tigger transposable element derived 3provided by MGI
Primary source
MGI:MGI:2681860
See related
Ensembl:ENSMUSG00000044390 AllianceGenome:MGI:2681860
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA binding activity. Predicted to be active in nucleus. Orthologous to human TIGD3 (tigger transposable element derived 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E14 (RPKM 3.2), whole brain E14.5 (RPKM 3.1) and 24 other tissues See more
Orthologs
human all
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Genomic context

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Location:
19 A; 19 4.34 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5941166..5944156, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5891138..5894128, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_45411 Neighboring gene FERM domain containing 8, opposite strand Neighboring gene FERM domain containing 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:5878208-5878317 Neighboring gene solute carrier family 25, member 45 Neighboring gene STARR-positive B cell enhancer ABC_E1522 Neighboring gene double PHD fingers 2 Neighboring gene STARR-positive B cell enhancer ABC_E7628 Neighboring gene predicted gene, 42067

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. VanBuren V, et al. Genome Res, 2002 Dec. PMID 12466305, Free PMC Article
  2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC60957, MGC67569

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tigger transposable element-derived protein 3
Names
tigger transposable element derived 3 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001362045.1 → NP_001348974.1  tigger transposable element-derived protein 3

    Status: VALIDATED

    Source sequence(s)
    AC142098
    Consensus CDS
    CCDS29483.1
    UniProtKB/Swiss-Prot
    Q7TM95
    Related
    ENSMUSP00000157880.2, ENSMUST00000236767.2
    Conserved Domains (3) summary
    pfam03221
    Location:76 → 133
    HTH_Tnp_Tc5; Tc5 transposase DNA-binding domain
    cl21459
    Location:6 → 57
    HTH; Helix-turn-helix domains
    cl21549
    Location:193 → 360
    rve; Integrase core domain

  2. NM_198634.2 → NP_941036.1  tigger transposable element-derived protein 3

    See identical proteins and their annotated locations for NP_941036.1

    Status: VALIDATED

    Source sequence(s)
    AC142098, BC055784, BQ558865
    Consensus CDS
    CCDS29483.1
    UniProtKB/Swiss-Prot
    Q7TM95
    Related
    ENSMUSP00000059302.5, ENSMUST00000055911.6
    Conserved Domains (3) summary
    pfam03221
    Location:76 → 133
    HTH_Tnp_Tc5; Tc5 transposase DNA-binding domain
    cl21459
    Location:6 → 57
    HTH; Helix-turn-helix domains
    cl21549
    Location:193 → 360
    rve; Integrase core domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    5941166..5944156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7TM95.1 GenPept UniProtKB/Swiss-Prot:Q7TM95

Gene LinkOut

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