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CG4822 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33170, updated on 4-Apr-2024

Summary

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Official Symbol
CG4822provided by FlyBase
Primary source
FLYBASE:FBgn0031220
Locus tag
Dmel_CG4822
See related
AllianceGenome:FB:FBgn0031220
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
DmCG4822; Dmel\CG4822
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in plasma membrane. Is expressed in adult head. Orthologous to human ABCG1 (ATP binding cassette subfamily G member 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See CG4822 in Genome Data Viewer
Location:
21B2-21B2; 2-0.5 cM
Exon count:
12
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (116970..121754, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (116970..121754, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene S-adenosylmethionine Synthetase Neighboring gene uncharacterized protein Neighboring gene NADH dehydrogenase (ubiquinone) 15 kDa subunit Neighboring gene antisense RNA:CR44969 Neighboring gene uncharacterized protein Neighboring gene Glutamine synthetase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutants of the white ABCG Transporter in Drosophila melanogaster Have Deficient Olfactory Learning and Cholesterol Homeostasis. Myers JL, et al. Int J Mol Sci, 2021 Nov 30. PMID 34884779, Free PMC Article
  2. A global timing mechanism regulates cell-type-specific wiring programmes. Jain S, et al. Nature, 2022 Mar. PMID 35197627
  3. RNAi experiments in D. melanogaster: solutions to the overlooked problem of off-targets shared by independent dsRNAs. Seinen E, et al. PLoS One, 2010 Oct 1. PMID 20957038, Free PMC Article
  4. Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster. Denecke S, et al. Proc Biol Sci, 2022 May 25. PMID 35582794, Free PMC Article
  5. Vesicle-Mediated Steroid Hormone Secretion in Drosophila melanogaster. Yamanaka N, et al. Cell, 2015 Nov 5. PMID 26544939, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4822-PA
CG4822-PB
CG4822-PC
CG4822-PD
CG4822-PE
CG4822-PF
CG4822-PG
CG4822-PH
CG4822-PI
NP_001033861.1
NP_001033862.1
NP_001033863.1
NP_001033864.1
NP_001259798.1
NP_608493.2
NP_722602.1
NP_722603.1
NP_722604.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    116970..121754 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001038772.2 → NP_001033861.1  uncharacterized protein Dmel_CG4822, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033861.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH11, Q9VPJ7
    Conserved Domains (3) summary
    cd03213
    Location:51 → 276
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:67 → 654
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:381 → 587
    ABC2_membrane; ABC-2 type transporter

  2. NM_164363.2 → NP_722602.1  uncharacterized protein Dmel_CG4822, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722602.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH11, Q9VPJ7
    Related
    FBpp0077814
    Conserved Domains (3) summary
    cd03213
    Location:51 → 276
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:67 → 654
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:381 → 587
    ABC2_membrane; ABC-2 type transporter

  3. NM_164364.3 → NP_722603.1  uncharacterized protein Dmel_CG4822, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722603.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH11, Q9VPJ7
    Related
    FBpp0077817
    Conserved Domains (3) summary
    cd03213
    Location:51 → 276
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:67 → 654
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:381 → 587
    ABC2_membrane; ABC-2 type transporter

  4. NM_134649.4 → NP_608493.2  uncharacterized protein Dmel_CG4822, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608493.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH11, Q9VPJ7
    Related
    FBpp0077816, FBtr0078158
    Conserved Domains (3) summary
    cd03213
    Location:51 → 276
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:67 → 654
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:381 → 587
    ABC2_membrane; ABC-2 type transporter

  5. NM_001272869.1 → NP_001259798.1  uncharacterized protein Dmel_CG4822, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259798.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBY9
    Conserved Domains (1) summary
    cl21455
    Location:51 → 108
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  6. NM_001038774.2 → NP_001033863.1  uncharacterized protein Dmel_CG4822, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033863.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2PDV9
    Conserved Domains (1) summary
    cl21455
    Location:51 → 139
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  7. NM_164365.2 → NP_722604.1  uncharacterized protein Dmel_CG4822, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722604.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH11, Q9VPJ7
    Related
    FBpp0077815
    Conserved Domains (3) summary
    cd03213
    Location:51 → 276
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:67 → 654
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:381 → 587
    ABC2_membrane; ABC-2 type transporter

  8. NM_001038773.2 → NP_001033862.1  uncharacterized protein Dmel_CG4822, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033862.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH11, Q9VPJ7
    Conserved Domains (3) summary
    cd03213
    Location:51 → 276
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:67 → 654
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:381 → 587
    ABC2_membrane; ABC-2 type transporter

  9. NM_001038775.2 → NP_001033864.1  uncharacterized protein Dmel_CG4822, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033864.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2PDV8
    Conserved Domains (1) summary
    cl21455
    Location:51 → 108
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PBY9 M9PBY9
Q2PDV8 Q2PDV8
Q2PDV9 Q2PDV9
Q8MQW6 Q8MQW6
Q9VPJ7 Q9VPJ7

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