U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Gm5127 predicted gene 5127 [ Mus musculus (house mouse) ]

Gene ID: 331493, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Gm5127provided by MGI
Official Full Name
predicted gene 5127provided by MGI
Primary source
MGI:MGI:3648285
See related
Ensembl:ENSMUSG00000073010 AllianceGenome:MGI:3648285
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG331493; B130007I08
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
X D; X 47.36 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (105626774..105754163)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (106583170..106710557)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene fibronectin type III domain containing 3C1 pseudogene Neighboring gene fibronectin type III domain containing 3C1 Neighboring gene STARR-seq mESC enhancer starr_47737 Neighboring gene cysteinyl leukotriene receptor 1 Neighboring gene predicted gene, 24622 Neighboring gene STARR-seq mESC enhancer starr_47738 Neighboring gene predicted gene 14877 Neighboring gene zinc finger protein 277 pseudogene Neighboring gene predicted gene, 24491 Neighboring gene SNRPN upstream reading frame protein pseudogene Neighboring gene 60S ribosomal protein L37 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of Rho protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein LOC331493

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033541.2 → NP_001028713.1  uncharacterized protein LOC331493

    See identical proteins and their annotated locations for NP_001028713.1

    Status: PREDICTED

    Source sequence(s)
    AK142438
    Consensus CDS
    CCDS30343.1
    UniProtKB/TrEMBL
    Q3UQH6
    Related
    ENSMUSP00000098855.4, ENSMUST00000101297.4
    Conserved Domains (2) summary
    cd14964
    Location:18 → 42
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:17 → 142
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    105626774..105754163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247617.3 → XP_011245919.1  uncharacterized protein LOC331493 isoform X1

    See identical proteins and their annotated locations for XP_011245919.1

    Conserved Domains (2) summary
    cd14964
    Location:31 → 57
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 156
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_011247618.2 → XP_011245920.1  uncharacterized protein LOC331493 isoform X1

    See identical proteins and their annotated locations for XP_011245920.1

    Conserved Domains (2) summary
    cd14964
    Location:31 → 57
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:31 → 156
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous