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Fam185a family with sequence similarity 185, member A [ Mus musculus (house mouse) ]

Gene ID: 330050, updated on 5-Mar-2024

Summary

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Official Symbol
Fam185aprovided by MGI
Official Full Name
family with sequence similarity 185, member Aprovided by MGI
Primary source
MGI:MGI:2140983
See related
Ensembl:ENSMUSG00000047221 AllianceGenome:MGI:2140983
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4631428I10
Summary
Orthologous to human FAM185A (family with sequence similarity 185 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 1.8), frontal lobe adult (RPKM 1.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Fam185a in Genome Data Viewer
Location:
5 A3; 5 9.83 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (21629861..21693269)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (21424861..21488271)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene gamma-secretase activating protein Neighboring gene coiled-coil domain containing 146 Neighboring gene STARR-positive B cell enhancer ABC_E6308 Neighboring gene VISTA enhancer mm186 Neighboring gene predicted gene, 50626 Neighboring gene STARR-positive B cell enhancer ABC_E6309 Neighboring gene STARR-positive B cell enhancer ABC_E6310 Neighboring gene STARR-seq mESC enhancer starr_12565 Neighboring gene STARR-positive B cell enhancer ABC_E3562 Neighboring gene fibrinogen-like protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E152 Neighboring gene F-box and leucine-rich repeat protein 13 Neighboring gene STARR-seq mESC enhancer starr_12566 Neighboring gene STARR-seq mESC enhancer starr_12567 Neighboring gene leucine rich repeat containing 17 Neighboring gene predicted gene 6543

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome. Corbo JC, et al. PLoS Genet, 2005 Aug. PMID 16110338, Free PMC Article
  2. ALS-linked loss of Cyclin-F function affects HSP90. Siebert A, et al. Life Sci Alliance, 2022 Sep 16. PMID 36114006, Free PMC Article
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein FAM185A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001424684.1 → NP_001411613.1  protein FAM185A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC157936, AC161484

  2. NM_177869.5 → NP_808537.2  protein FAM185A isoform 1

    See identical proteins and their annotated locations for NP_808537.2

    Status: VALIDATED

    Source sequence(s)
    AC157936
    Consensus CDS
    CCDS39022.1
    UniProtKB/Swiss-Prot
    Q7TPD2, Q8C6A4
    Related
    ENSMUSP00000058333.5, ENSMUST00000056045.5
    Conserved Domains (2) summary
    pfam13944
    Location:120 → 208
    Calycin_like; Calycin-like beta-barrel domain
    cl23960
    Location:130 → 302
    DUF2807; Putative auto-transporter adhesin, head GIN domain

RNA

  1. NR_188850.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157936

  2. NR_188851.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157936

  3. NR_188852.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157936

  4. NR_188853.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157936

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    21629861..21693269
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011249773.2 → XP_011248075.1  protein FAM185A isoform X2

    Conserved Domains (1) summary
    cl23960
    Location:133 → 255
    DUF4097; Putative adhesin

RNA

  1. XR_003955661.2 RNA Sequence

  2. XR_003955662.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7TPD2.1 GenPept UniProtKB/Swiss-Prot:Q7TPD2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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