U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Accs 1-aminocyclopropane-1-carboxylate synthase (inactive) [ Mus musculus (house mouse) ]

Gene ID: 329470, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Accsprovided by MGI
Official Full Name
1-aminocyclopropane-1-carboxylate synthase (inactive)provided by MGI
Primary source
MGI:MGI:1919717
See related
Ensembl:ENSMUSG00000040272 AllianceGenome:MGI:1919717
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Phacs; 2610203E10Rik
Summary
Predicted to enable identical protein binding activity and transaminase activity. Predicted to be involved in cellular amino acid metabolic process. Orthologous to human ACCS (1-aminocyclopropane-1-carboxylate synthase homolog (inactive)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 2.8), CNS E11.5 (RPKM 2.6) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
2 E1; 2 51.62 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (93663812..93680343, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (93833467..93849997, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene aristaless-like homeobox 4 Neighboring gene exostosin glycosyltransferase 2 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:93662723-93662832 Neighboring gene 1-aminocyclopropane-1-carboxylate synthase (inactive)-like Neighboring gene predicted gene, 54116 Neighboring gene STARR-seq mESC enhancer starr_05168 Neighboring gene predicted gene 1335

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC48140

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables transaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in amino acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
1-aminocyclopropane-1-carboxylate synthase-like protein 1
Names
1-aminocyclopropane-1-carboxylate synthase (non-functional)
1-aminocyclopropane-1-carboxylate synthase homolog
ACC synthase-like protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290782.1 → NP_001277711.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform a

    See identical proteins and their annotated locations for NP_001277711.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    AK011867, AL732472, BC039569
    Consensus CDS
    CCDS71105.1
    UniProtKB/Swiss-Prot
    A2AIG8, Q8CHS6
    Related
    ENSMUSP00000106877.2, ENSMUST00000111246.8
    Conserved Domains (1) summary
    PLN02450
    Location:81 → 483
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  2. NM_183220.3 → NP_899043.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform b

    See identical proteins and their annotated locations for NP_899043.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a.
    Source sequence(s)
    AK011867, AL732472, BC039569
    Consensus CDS
    CCDS16457.1
    UniProtKB/Swiss-Prot
    A2AIG8
    Related
    ENSMUSP00000036268.9, ENSMUST00000041593.15
    Conserved Domains (1) summary
    PLN02450
    Location:58 → 460
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    93663812..93680343 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011239625.2 → XP_011237927.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X4

    See identical proteins and their annotated locations for XP_011237927.1

    Conserved Domains (1) summary
    PLN02450
    Location:10 → 247
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  2. XM_036162322.1 → XP_036018215.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A2AIG8, Q8CHS6
    Conserved Domains (1) summary
    PLN02450
    Location:81 → 483
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  3. XM_006499761.4 → XP_006499824.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006499824.1

    UniProtKB/Swiss-Prot
    A2AIG8, Q8CHS6
    Conserved Domains (1) summary
    PLN02450
    Location:81 → 483
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  4. XM_006499760.4 → XP_006499823.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006499823.1

    UniProtKB/Swiss-Prot
    A2AIG8, Q8CHS6
    Conserved Domains (1) summary
    PLN02450
    Location:81 → 483
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  5. XM_006499764.3 → XP_006499827.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X2

    See identical proteins and their annotated locations for XP_006499827.1

    UniProtKB/Swiss-Prot
    A2AIG8
    Conserved Domains (1) summary
    PLN02450
    Location:58 → 460
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  6. XM_006499763.3 → XP_006499826.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X2

    See identical proteins and their annotated locations for XP_006499826.1

    UniProtKB/Swiss-Prot
    A2AIG8
    Conserved Domains (1) summary
    PLN02450
    Location:58 → 460
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  7. XM_006499765.3 → XP_006499828.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X2

    See identical proteins and their annotated locations for XP_006499828.1

    UniProtKB/Swiss-Prot
    A2AIG8
    Conserved Domains (1) summary
    PLN02450
    Location:58 → 460
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  8. XM_006499766.3 → XP_006499829.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X2

    See identical proteins and their annotated locations for XP_006499829.1

    UniProtKB/Swiss-Prot
    A2AIG8
    Related
    ENSMUSP00000065389.5, ENSMUST00000068513.11
    Conserved Domains (1) summary
    PLN02450
    Location:58 → 460
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  9. XM_006499768.3 → XP_006499831.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X4

    See identical proteins and their annotated locations for XP_006499831.1

    Conserved Domains (1) summary
    PLN02450
    Location:10 → 247
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  10. XM_030251803.1 → XP_030107663.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X4

    Conserved Domains (1) summary
    PLN02450
    Location:10 → 247
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  11. XM_030251804.1 → XP_030107664.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X4

    Conserved Domains (1) summary
    PLN02450
    Location:10 → 247
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  12. XM_030251802.1 → XP_030107662.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X4

    Conserved Domains (1) summary
    PLN02450
    Location:10 → 247
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  13. XM_036162323.1 → XP_036018216.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X2

    Conserved Domains (1) summary
    PLN02450
    Location:58 → 460
    PLN02450; 1-aminocyclopropane-1-carboxylate synthase

  14. XM_011239623.1 → XP_011237925.1  1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X3

    See identical proteins and their annotated locations for XP_011237925.1

    Conserved Domains (1) summary
    cd00609
    Location:62 → 434
    AAT_like; Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine ...

RNA

  1. XR_374480.5 RNA Sequence

  2. XR_004940649.1 RNA Sequence

  3. XR_004940650.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2AIG8.1 GenPept UniProtKB/Swiss-Prot:A2AIG8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous