U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp532 zinc finger protein 532 [ Mus musculus (house mouse) ]

Gene ID: 328977, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Zfp532provided by MGI
Official Full Name
zinc finger protein 532provided by MGI
Primary source
MGI:MGI:3036282
See related
Ensembl:ENSMUSG00000042439 AllianceGenome:MGI:3036282
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf532; mKIAA1629; C530030I18Rik
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Is expressed in female reproductive system and urinary system. Orthologous to human ZNF532 (zinc finger protein 532). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E14 (RPKM 12.0), whole brain E14.5 (RPKM 12.0) and 22 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
18 E1; 18 38.91 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (65713301..65822514)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (65580230..65689443)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118568360 Neighboring gene predicted gene, 41759 Neighboring gene STARR-seq mESC enhancer starr_44834 Neighboring gene STARR-seq mESC enhancer starr_44835 Neighboring gene STARR-seq mESC enhancer starr_44838 Neighboring gene zinc finger protein 592 pseudogene Neighboring gene O-acyltransferase like Neighboring gene predicted gene, 54022

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose-induced apoptosis and pyroptosis by regulating the miR-20b-5p/STAT3 axis. Liang GH, et al. J Diabetes Investig, 2022 May. PMID 34839589, Free PMC Article
  2. Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation. Barnes CE, et al. Mol Omics, 2022 Jan 17. PMID 34709266, Free PMC Article
  3. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
  4. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
  5. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose-induced apoptosis and pyroptosis by regulating the miR-20b-5p/STAT3 axis.
    Title: CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose-induced apoptosis and pyroptosis by regulating the miR-20b-5p/STAT3 axis.
Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein 532

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361051.1 → NP_001347980.1  zinc finger protein 532 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC124578, AC132307
    Consensus CDS
    CCDS89265.1
    UniProtKB/TrEMBL
    S4R2I9
    Conserved Domains (3) summary
    sd00017
    Location:1024 → 1044
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16622
    Location:1202 → 1230
    zf-C2H2_11; zinc-finger C2H2-type
    cl25756
    Location:150 → 360
    BASP1; Brain acid soluble protein 1 (BASP1 protein)

  2. NM_001361052.1 → NP_001347981.1  zinc finger protein 532 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC124578, AC132307
    Consensus CDS
    CCDS89265.1
    UniProtKB/TrEMBL
    S4R2I9
    Conserved Domains (3) summary
    sd00017
    Location:1024 → 1044
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16622
    Location:1202 → 1230
    zf-C2H2_11; zinc-finger C2H2-type
    cl25756
    Location:150 → 360
    BASP1; Brain acid soluble protein 1 (BASP1 protein)

  3. NM_001361053.1 → NP_001347982.1  zinc finger protein 532 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC124578, AC132307
    Consensus CDS
    CCDS89265.1
    UniProtKB/TrEMBL
    S4R2I9
    Related
    ENSMUSP00000157481.2, ENSMUST00000237553.2
    Conserved Domains (3) summary
    sd00017
    Location:1024 → 1044
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16622
    Location:1202 → 1230
    zf-C2H2_11; zinc-finger C2H2-type
    cl25756
    Location:150 → 360
    BASP1; Brain acid soluble protein 1 (BASP1 protein)

  4. NM_207255.2 → NP_997138.1  zinc finger protein 532 isoform 2

    See identical proteins and their annotated locations for NP_997138.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1.
    Source sequence(s)
    AA253972, AK163498, AK163988, BC067032
    Consensus CDS
    CCDS29307.1
    UniProtKB/Swiss-Prot
    Q504Z6, Q6NXK2, Q6ZPL1
    Related
    ENSMUSP00000036582.5, ENSMUST00000049016.12
    Conserved Domains (3) summary
    sd00017
    Location:753 → 772
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13912
    Location:999 → 1021
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:934 → 962
    zf-C2H2_11; zinc-finger C2H2-type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    65713301..65822514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6NXK2.1 GenPept UniProtKB/Swiss-Prot:Q6NXK2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous