U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp414 zinc finger protein 414 [ Mus musculus (house mouse) ]

Gene ID: 328801, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Zfp414provided by MGI
Official Full Name
zinc finger protein 414provided by MGI
Primary source
MGI:MGI:1915641
See related
Ensembl:ENSMUSG00000073423 AllianceGenome:MGI:1915641
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf414; 0610030H11Rik
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Is expressed in several structures, including brain; genitourinary system; heart; hemolymphoid system gland; and liver. Orthologous to human ZNF414 (zinc finger protein 414). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 36.8), thymus adult (RPKM 34.0) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Zfp414 in Genome Data Viewer
Location:
17 B1; 17 17.98 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33848066..33850690)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (33629092..33631716)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 10 Neighboring gene myosin IF Neighboring gene STARR-seq mESC enhancer starr_42407 Neighboring gene STARR-seq mESC enhancer starr_42408 Neighboring gene STARR-seq mESC enhancer starr_42409 Neighboring gene PML-RAR alpha-regulated adaptor molecule 1 Neighboring gene heterogeneous nuclear ribonucleoprotein M Neighboring gene STARR-positive B cell enhancer ABC_E10946

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. PRAM-1 is required for optimal integrin-dependent neutrophil function. Clemens RA, et al. Mol Cell Biol, 2004 Dec. PMID 15572693, Free PMC Article
  2. Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5. Abe K, et al. Mamm Genome, 2004 Apr. PMID 15112104
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Markers

Potential readthrough

Included gene: Pram1

Homology

Clone Names

  • MGC49274

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein 414
Names
zinc finger, C2H2 type containing protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026712.3 → NP_080988.1  zinc finger protein 414

    See identical proteins and their annotated locations for NP_080988.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the functional protein.
    Source sequence(s)
    AI844570, BC119044, BY737447
    Consensus CDS
    CCDS37568.1
    UniProtKB/Swiss-Prot
    Q8CHU9, Q9DCK4
    UniProtKB/TrEMBL
    Q14A93
    Related
    ENSMUSP00000073259.6, ENSMUST00000073570.12
    Conserved Domains (2) summary
    sd00017
    Location:104 → 123
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam15909
    Location:100 → 194
    zf-C2H2_8; C2H2-type zinc ribbon

RNA

  1. NR_034153.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) includes an alternate exon in the 5' region, compared to variant 1. This transcript is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AI466623, AI844570, BY737447, CX218166
    Related
    ENSMUST00000166627.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    33848066..33850690
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DCK4.1 GenPept UniProtKB/Swiss-Prot:Q9DCK4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous