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Mettl24 methyltransferase like 24 [ Mus musculus (house mouse) ]

Gene ID: 327747, updated on 5-Mar-2024

Summary

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Official Symbol
Mettl24provided by MGI
Official Full Name
methyltransferase like 24provided by MGI
Primary source
MGI:MGI:3045338
See related
Ensembl:ENSMUSG00000045555 AllianceGenome:MGI:3045338
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9030224M15Rik
Summary
Predicted to enable methyltransferase activity. Predicted to act upstream of or within methylation. Predicted to be located in extracellular region. Orthologous to human METTL24 (methyltransferase like 24). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in ovary adult (RPKM 4.0), lung adult (RPKM 3.9) and 17 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10 B1; 10 22.02 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (40558447..40687080)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (40682445..40812733)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_26428 Neighboring gene solute carrier family 22 (organic cation transporter), member 16 Neighboring gene D-aspartate oxidase Neighboring gene STARR-seq mESC enhancer starr_26430 Neighboring gene STARR-seq mESC enhancer starr_26431 Neighboring gene STARR-seq mESC enhancer starr_26432 Neighboring gene STARR-seq mESC enhancer starr_26433 Neighboring gene STARR-seq mESC enhancer starr_26435 Neighboring gene cell division cycle 40 Neighboring gene STARR-positive B cell enhancer ABC_E2320 Neighboring gene WASP family, member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (4) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
probable methyltransferase-like protein 24
Names
UPF0624 protein C6orf186 homolog
methyltransferase-like protein 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177793.3 → NP_808461.1  probable methyltransferase-like protein 24 precursor

    See identical proteins and their annotated locations for NP_808461.1

    Status: PROVISIONAL

    Source sequence(s)
    AK033488
    Consensus CDS
    CCDS23799.1
    UniProtKB/Swiss-Prot
    Q8CCB5
    Related
    ENSMUSP00000049997.4, ENSMUST00000058747.4
    Conserved Domains (1) summary
    cl17173
    Location:178 → 295
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    40558447..40687080
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245130.2 → XP_030100990.1  probable methyltransferase-like protein 24 isoform X5

    Conserved Domains (1) summary
    cl17173
    Location:1 → 101
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  2. XM_030245132.2 → XP_030100992.1  probable methyltransferase-like protein 24 isoform X5

    Conserved Domains (1) summary
    cl17173
    Location:1 → 101
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  3. XM_006512765.5 → XP_006512828.1  probable methyltransferase-like protein 24 isoform X1

    Conserved Domains (1) summary
    cl17173
    Location:184 → 309
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  4. XM_006512767.5 → XP_006512830.1  probable methyltransferase-like protein 24 isoform X3

  5. XM_006512768.5 → XP_006512831.1  probable methyltransferase-like protein 24 isoform X4

  6. XM_006512766.5 → XP_006512829.1  probable methyltransferase-like protein 24 isoform X2

    Conserved Domains (1) summary
    cl17173
    Location:137 → 262
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  7. XM_036155823.1 → XP_036011716.1  probable methyltransferase-like protein 24 isoform X5

    Conserved Domains (1) summary
    cl17173
    Location:1 → 101
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  8. XM_030245131.2 → XP_030100991.1  probable methyltransferase-like protein 24 isoform X5

    Conserved Domains (1) summary
    cl17173
    Location:1 → 101
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CCB5.1 GenPept UniProtKB/Swiss-Prot:Q8CCB5

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