Fpr-rs7 formyl peptide receptor, related sequence 7 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Fpr-rs7provided by MGI
Official Full Name: formyl peptide receptor, related sequence 7provided by MGI
Primary source: MGI:MGI:2448177
See related: Ensembl:ENSMUSG00000071276 AllianceGenome:MGI:2448177
Gene type: protein coding
RefSeq status: MODEL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Enables N-formyl peptide receptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Orthologous to human FPR3 (formyl peptide receptor 3). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (20333472..20334488, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (20113210..20114226, complement)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Alleles of this type are documented at Mouse Genome Informatics (MGI)

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables N-formyl peptide receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables N-formyl peptide receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables amyloid-beta binding	ISO Inferred from Sequence Orthology more info
enables complement receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables scavenger receptor binding	ISO Inferred from Sequence Orthology more info
enables signaling receptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in complement receptor mediated signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in inflammatory response	IBA Inferred from Biological aspect of Ancestor more info
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cytosolic calcium ion concentration	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IC Inferred by Curator more info	PubMed
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

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The following sections contain reference sequences that belong to a specific genome build. Explain

The following Reference Sequences have been suppressed. Explain

NM_177317.1: Suppressed sequence

Description

NM_177317.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.