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Ccdc158 coiled-coil domain containing 158 [ Mus musculus (house mouse) ]

Gene ID: 320696, updated on 5-Mar-2024

Summary

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Official Symbol
Ccdc158provided by MGI
Official Full Name
coiled-coil domain containing 158provided by MGI
Primary source
MGI:MGI:2444555
See related
Ensembl:ENSMUSG00000050050 AllianceGenome:MGI:2444555
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4932413O14Rik
Summary
Orthologous to human CCDC158 (coiled-coil domain containing 158). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 12.5) See more
Orthologs
human all
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Genomic context

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Location:
5 E2; 5 47.23 cM
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (92756096..92823327, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (92608237..92675472, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_13648 Neighboring gene family with sequence similarity 47, member E Neighboring gene VISTA enhancer mm187 Neighboring gene starch binding domain 1 Neighboring gene STARR-seq mESC enhancer starr_13649 Neighboring gene shroom family member 3 Neighboring gene STARR-seq mESC enhancer starr_13650 Neighboring gene STARR-seq mESC enhancer starr_13651 Neighboring gene STARR-seq mESC enhancer starr_13653 Neighboring gene microRNA 1961 Neighboring gene STARR-seq mESC enhancer starr_13654 Neighboring gene STARR-seq mESC enhancer starr_13657 Neighboring gene STARR-seq mESC enhancer starr_13658 Neighboring gene VISTA enhancer mm397 Neighboring gene predicted gene, 36764 Neighboring gene ribosomal protein L9 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 158

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360018.1 → NP_001346947.1  coiled-coil domain-containing protein 158 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
    Source sequence(s)
    AC123850, AC124560, BC137976
    UniProtKB/TrEMBL
    B2RQL1
    Conserved Domains (1) summary
    cl25732
    Location:1 → 1113
    SMC_N; RecF/RecN/SMC N terminal domain

  2. NM_001360019.1 → NP_001346948.1  coiled-coil domain-containing protein 158 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, 3' UTR, and 3' coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct C-terminus compared to isoform a. Variants 3 and 4 both encode the same isoform (c).
    Source sequence(s)
    AC124560, AK160895
    Consensus CDS
    CCDS89939.1
    Related
    ENSMUSP00000117894.2, ENSMUST00000151180.8
    Conserved Domains (1) summary
    pfam15921
    Location:1 → 342
    CCDC158; Coiled-coil domain-containing protein 158

  3. NM_001360020.1 → NP_001346949.1  coiled-coil domain-containing protein 158 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, 3' UTR, and 3' coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct C-terminus compared to isoform a. Variants 3 and 4 both encode the same isoform (c).
    Source sequence(s)
    AC124560
    Consensus CDS
    CCDS89939.1
    Related
    ENSMUSP00000123259.2, ENSMUST00000150359.2
    Conserved Domains (1) summary
    pfam15921
    Location:1 → 342
    CCDC158; Coiled-coil domain-containing protein 158

  4. NM_177230.3 → NP_796204.1  coiled-coil domain-containing protein 158 isoform b

    See identical proteins and their annotated locations for NP_796204.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AC123850, AC124560
    Consensus CDS
    CCDS19434.1
    UniProtKB/Swiss-Prot
    Q3TU97, Q8CDI6
    Related
    ENSMUSP00000063050.4, ENSMUST00000060930.10
    Conserved Domains (1) summary
    pfam15921
    Location:1 → 1109
    CCDC158; Coiled-coil domain-containing protein 158

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    92756096..92823327 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534992.4 → XP_006535055.1  coiled-coil domain-containing protein 158 isoform X3

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 1106
    CCDC158; Coiled-coil domain-containing protein 158

  2. XM_030254576.2 → XP_030110436.1  coiled-coil domain-containing protein 158 isoform X7

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 1060
    CCDC158; Coiled-coil domain-containing protein 158

  3. XM_006534994.4 → XP_006535057.1  coiled-coil domain-containing protein 158 isoform X5

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 1077
    CCDC158; Coiled-coil domain-containing protein 158

  4. XM_006534993.4 → XP_006535056.1  coiled-coil domain-containing protein 158 isoform X4

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 1023
    CCDC158; Coiled-coil domain-containing protein 158

  5. XM_006534991.4 → XP_006535054.1  coiled-coil domain-containing protein 158 isoform X2

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 1050
    CCDC158; Coiled-coil domain-containing protein 158

  6. XM_006534996.4 → XP_006535059.1  coiled-coil domain-containing protein 158 isoform X9

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 970
    CCDC158; Coiled-coil domain-containing protein 158

  7. XM_006534989.5 → XP_006535052.1  coiled-coil domain-containing protein 158 isoform X1

    See identical proteins and their annotated locations for XP_006535052.1

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 1054
    CCDC158; Coiled-coil domain-containing protein 158

  8. XM_006534988.4 → XP_006535051.1  coiled-coil domain-containing protein 158 isoform X1

    See identical proteins and their annotated locations for XP_006535051.1

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 1054
    CCDC158; Coiled-coil domain-containing protein 158

  9. XM_006534995.4 → XP_006535058.1  coiled-coil domain-containing protein 158 isoform X6

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 1001
    CCDC158; Coiled-coil domain-containing protein 158

  10. XM_006534997.1 → XP_006535060.1  coiled-coil domain-containing protein 158 isoform X10

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 742
    CCDC158; Coiled-coil domain-containing protein 158

  11. XM_011249479.3 → XP_011247781.1  coiled-coil domain-containing protein 158 isoform X8

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 1053
    CCDC158; Coiled-coil domain-containing protein 158

  12. XM_030254577.2 → XP_030110437.1  coiled-coil domain-containing protein 158 isoform X11

    Conserved Domains (1) summary
    pfam15921
    Location:1 → 342
    CCDC158; Coiled-coil domain-containing protein 158
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CDI6.1 GenPept UniProtKB/Swiss-Prot:Q8CDI6

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