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Ccdc169 coiled-coil domain containing 169 [ Mus musculus (house mouse) ]

Gene ID: 320604, updated on 5-Mar-2024

Summary

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Official Symbol
Ccdc169provided by MGI
Official Full Name
coiled-coil domain containing 169provided by MGI
Primary source
MGI:MGI:2444356
See related
Ensembl:ENSMUSG00000048655 AllianceGenome:MGI:2444356
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A730037C10Rik
Summary
Orthologous to human CCDC169 (coiled-coil domain containing 169). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 8.5) and liver E14 (RPKM 1.2) See more
Orthologs
human all
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Genomic context

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Location:
3 C; 3 26.53 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (55044760..55082671)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (55137339..55175250)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4931419H13 gene Neighboring gene STARR-seq mESC enhancer starr_07692 Neighboring gene cyclin A1 Neighboring gene STARR-seq mESC enhancer starr_07693 Neighboring gene STARR-seq mESC enhancer starr_07694 Neighboring gene spartin Neighboring gene spermatogenesis and oogenesis specific basic helix-loop-helix 2 Neighboring gene STARR-seq mESC enhancer starr_07696 Neighboring gene doublecortin-like kinase 1 Neighboring gene predicted gene, 25132

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
  5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 169

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290138.1 → NP_001277067.1  coiled-coil domain-containing protein 169 isoform b

    See identical proteins and their annotated locations for NP_001277067.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Both variants 2 and 3 encode isoform b.
    Source sequence(s)
    AC111132, AI467609, AK042903
    Consensus CDS
    CCDS79907.1
    UniProtKB/Swiss-Prot
    Q8BXX9
    Related
    ENSMUSP00000049698.5, ENSMUST00000052904.11
    Conserved Domains (1) summary
    pfam15372
    Location:1 → 99
    DUF4600; Domain of unknown function (DUF4600)

  2. NM_001290141.1 → NP_001277070.1  coiled-coil domain-containing protein 169 isoform b

    See identical proteins and their annotated locations for NP_001277070.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Both variants 2 and 3 encode isoform b.
    Source sequence(s)
    AC111132, AI467609, AK042903, AK076919
    Consensus CDS
    CCDS79907.1
    UniProtKB/Swiss-Prot
    Q8BXX9
    Conserved Domains (1) summary
    pfam15372
    Location:1 → 99
    DUF4600; Domain of unknown function (DUF4600)

  3. NM_177203.3 → NP_796177.2  coiled-coil domain-containing protein 169 isoform a

    See identical proteins and their annotated locations for NP_796177.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    AI467609, AK042903, AK076919
    Consensus CDS
    CCDS17357.2
    UniProtKB/Swiss-Prot
    Q8BVQ6, Q8BXX9
    UniProtKB/TrEMBL
    D3YWT6
    Related
    ENSMUSP00000054771.8, ENSMUST00000061099.14
    Conserved Domains (1) summary
    pfam15372
    Location:55 → 181
    DUF4600; Domain of unknown function (DUF4600)

RNA

  1. NR_110776.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) contains an additional internal exon in the 3' region, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC111132, AI467609, AK042903, AK076919

  2. NR_110780.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks an exon in the 5' region and includes an additional internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AI467609, AK042903, AK076919, BC171976

  3. NR_110781.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks an exon in the 5' region and includes two additional internal exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AI467609, AK042903, AK076919, BC171978

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    55044760..55082671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501572.5 → XP_006501635.1  coiled-coil domain-containing protein 169 isoform X2

    UniProtKB/TrEMBL
    D3YWT6
    Related
    ENSMUSP00000112414.3, ENSMUST00000118963.9
    Conserved Domains (1) summary
    pfam15372
    Location:55 → 181
    DUF4600; Domain of unknown function (DUF4600)

  2. XM_006501571.5 → XP_006501634.1  coiled-coil domain-containing protein 169 isoform X1

    UniProtKB/TrEMBL
    D3YWT6
    Conserved Domains (1) summary
    pfam15372
    Location:55 → 181
    DUF4600; Domain of unknown function (DUF4600)

  3. XM_017319613.2 → XP_017175102.1  coiled-coil domain-containing protein 169 isoform X3

    UniProtKB/Swiss-Prot
    Q8BXX9
    Conserved Domains (1) summary
    pfam15372
    Location:1 → 99
    DUF4600; Domain of unknown function (DUF4600)

  4. XM_017319614.2 → XP_017175103.1  coiled-coil domain-containing protein 169 isoform X3

    UniProtKB/Swiss-Prot
    Q8BXX9
    Conserved Domains (1) summary
    pfam15372
    Location:1 → 99
    DUF4600; Domain of unknown function (DUF4600)

  5. XM_006501575.3 → XP_006501638.1  coiled-coil domain-containing protein 169 isoform X3

    See identical proteins and their annotated locations for XP_006501638.1

    UniProtKB/Swiss-Prot
    Q8BXX9
    Conserved Domains (1) summary
    pfam15372
    Location:1 → 99
    DUF4600; Domain of unknown function (DUF4600)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BXX9.2 GenPept UniProtKB/Swiss-Prot:Q8BXX9

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